PIP3 plasma membrane intrinsic protein 3 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Gene symbol: PIP3
Gene description: plasma membrane intrinsic protein 3
Primary source: Araport:AT4G35100
Locus tag: AT4G35100
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: PIP2;7; PIP3A; PLASMA MEMBRANE INTRINSIC PROTEIN 2;7; plasma membrane intrinsic protein 3; PLASMA MEMBRANE INTRINSIC PROTEIN 3; PLASMA MEMBRANE INTRINSIC PROTEIN 3A; SIMIP; T12J5.9
Summary: a member of the plasma membrane intrinsic protein PIP. functions as aquaporin. Salt-stress-inducible MIP
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

PAMP-INDUCED SECRETED PEPTIDE 3 modulates salt tolerance through RECEPTOR-LIKE KINASE 7 in plants.
Title: PAMP-INDUCED SECRETED PEPTIDE 3 modulates salt tolerance through RECEPTOR-LIKE KINASE 7 in plants.
TSPO physically interacts with PIP2;7 at the endoplasmic reticulum and Golgi membranes.
Title: The Arabidopsis abiotic stress-induced TSPO-related protein reduces cell-surface expression of the aquaporin PIP2;7 through protein-protein interactions and autophagic degradation.
Post-Golgi trafficking of PIP2;7 involves interactions with Qc-SNARE SYP61 and Qa-SNARE SYP121. The proper delivery of PIP2;7 to the plasma membrane depends on the activity of the two SNAREs, and that the SNAREs colocalize and physically interact.
Title: Arabidopsis SNAREs SYP61 and SYP121 coordinate the trafficking of plasma membrane aquaporin PIP2;7 to modulate the cell membrane water permeability.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_001203991.1

Function	Evidence Code	Pubs
enables mRNA binding	HDA more info	PubMed
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables water channel activity	IDA Inferred from Direct Assay more info	PubMed
enables water channel activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within water transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	HDA more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info
located_in plasma membrane	TAS Traceable Author Statement more info	PubMed
located_in plasmodesma	HDA more info	PubMed
located_in vacuole	HDA more info	PubMed

NP_001190920.1

plasma membrane intrinsic protein 3 (PIP3); CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 2;8 (TAIR:AT2G16850.1).

NP_195236.1

plasma membrane intrinsic protein 3 (PIP3); FUNCTIONS IN: water channel activity; INVOLVED IN: response to salt stress, transport; LOCATED IN: anchored to plasma membrane, nucleus, plasma membrane, vacuole, membrane; EXPRESSED IN: guard cell, cultured cell, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 2;8 (TAIR:AT2G16850.1); Has 10883 Blast hits to 10871 proteins in 2222 species: Archae - 81; Bacteria - 5172; Metazoa - 1469; Fungi - 457; Plants - 2516; Viruses - 2; Other Eukaryotes - 1186 (source: NCBI BLink).