NRPB9A RNA polymerases M/15 Kd subunit [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: NRPB9A
Gene description: RNA polymerases M/15 Kd subunit
Primary source: Araport:AT3G16980
Locus tag: AT3G16980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: NRPD9A; NRPE9A
Summary: One of two highly similar, non-catalytic subunits common to nuclear DNA-directed RNA polymerases II, IV and V; homologous to budding yeast RPB9. Appears to be redundant with At4g16265
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Genomic context

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See NRPB9A in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 4

Sequence:: Chromosome: 3; NC_003074.8 (5794392..5795827)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results reveal a role for the ninth subunit, NRP(B/D/E) 9a and NRP(B/D/E) 9b, in RNA silencing and demonstrate that subunit diversity generates functionally distinct subtypes of RNA polymerases II and V. [NRPE9A]
Title: Functional consequences of subunit diversity in RNA polymerases II and V.
These results reveal a role for the ninth subunit in RNA silencing and demonstrate that subunit diversity generates functionally distinct subtypes of RNA polymerases II and V.
Title: Functional consequences of subunit diversity in RNA polymerases II and V.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_112574.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of RNA polymerase II, core complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase V complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: RNA polymerases M/15 Kd subunit

NP_188323.1

NRPB9A; FUNCTIONS IN: DNA-directed RNA polymerase activity, transcription regulator activity, DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: transcription, regulation of transcription; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, core complex; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, TFIIS-type (InterPro:IPR001222), DNA-directed RNA polymerase, M/15kDa subunit (InterPro:IPR001529), DNA-directed RNA polymerase M, 15kDa subunit, conserved site (InterPro:IPR019761); BEST Arabidopsis thaliana protein match is: RNA polymerases M/15 Kd subunit (TAIR:AT4G16265.1); Has 955 Blast hits to 950 proteins in 294 species: Archae - 163; Bacteria - 0; Metazoa - 246; Fungi - 231; Plants - 130; Viruses - 0; Other Eukaryotes - 185 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

5794392..5795827

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112574.3 → NP_188323.1 RNA polymerases M/15 Kd subunit [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188323.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q6NLH0

UniProtKB/TrEMBL

A0A178VJH2, A0A5S9XD10, A0A5S9XSY5

Conserved Domains (2) summary

COG1594
Location:3 → 114

RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]

cd10508
Location:64 → 113

Zn-ribbon_RPB9; C-terminal zinc ribbon domain of RPB9 subunit of RNA polymerase II