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    PUR ALPHA-1 purin-rich alpha 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817768, updated on 15-Oct-2023

    Summary

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    Gene symbol
    PUR ALPHA-1
    Gene description
    purin-rich alpha 1
    Primary source
    Araport:AT2G32080
    Locus tag
    AT2G32080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22D22.17; F22D22_17; purin-rich alpha 1
    Summary
    similar to the conserved animal nuclear protein PUR alpha which was implicated in the control of gene transcription and DNA replication
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (13642237..13644421, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cell cycle control-like protein (DUF572) Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene Lactoylglutathione lyase / glyoxalase I family protein Neighboring gene ovate family protein 16 Neighboring gene tRNA-Asn

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Internal telomeric repeats and 'TCP domain' protein-binding sites co-operate to regulate gene expression in Arabidopsis thaliana cycling cells. Trémousaygue D, et al. Plant J, 2003 Mar. PMID 12631321
    2. Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. Majerská J, et al. Protoplasma, 2017 Jul. PMID 27853871
    3. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358
    4. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128768.3
    NM_179851.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables purine-rich negative regulatory element binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome HDA PubMed 

    General protein information

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    Preferred Names
    purin-rich alpha 1
    NP_565736.1
    • purin-rich alpha 1 (PUR ALPHA-1); FUNCTIONS IN: nucleic acid binding; INVOLVED IN: response to cadmium ion; LOCATED IN: cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PUR-alpha/beta/gamma, DNA/RNA-binding (InterPro:IPR006628); Has 941 Blast hits to 931 proteins in 224 species: Archae - 0; Bacteria - 0; Metazoa - 285; Fungi - 149; Plants - 385; Viruses - 0; Other Eukaryotes - 122 (source: NCBI BLink).
    NP_850182.1
    • purin-rich alpha 1 (PUR ALPHA-1); FUNCTIONS IN: nucleic acid binding; INVOLVED IN: response to cadmium ion; LOCATED IN: cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PUR-alpha/beta/gamma, DNA/RNA-binding (InterPro:IPR006628); Has 588 Blast hits to 332 proteins in 74 species: Archae - 0; Bacteria - 31; Metazoa - 438; Fungi - 0; Plants - 102; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13642237..13644421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179851.3 → NP_850182.1  purin-rich alpha 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850182.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVW2, A0A5S9X392
      Conserved Domains (1) summary
      pfam04845
      Location:30 → 273
      PurA; PurA ssDNA and RNA-binding protein

    2. NM_128768.3 → NP_565736.1  purin-rich alpha 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565736.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W590, Q9SKZ1, Q9XHC4
      UniProtKB/TrEMBL
      A0A178VXA3
      Conserved Domains (1) summary
      pfam04845
      Location:30 → 274
      PurA; PurA ssDNA and RNA-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SKZ1.2

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