pop1 POP1 homolog, ribonuclease P/MRP subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pop1provided by ZNC
Official Full Name: POP1 homolog, ribonuclease P/MRP subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-120911-1
See related: AllianceGenome:ZFIN:ZDB-GENE-120911-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA processing. Predicted to act upstream of or within tRNA 5'-leader removal. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Human ortholog(s) of this gene implicated in anauxetic dysplasia 2. Orthologous to human POP1 (POP1 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (54674327..54687178)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (54865718..54878937)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G40862 (e-PCR)
- UniSTS:7439

z992 (e-PCR), detects polymorphism
- UniSTS:205112

G39566 (e-PCR)
- UniSTS:33204

G40760 (e-PCR)
- UniSTS:46028

z9269 (e-PCR), detects polymorphism
- UniSTS:205284

z13925 (e-PCR), detects polymorphism
- UniSTS:205295

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within tRNA 5'-leader removal	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of nucleolar ribonuclease P complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonuclease MRP complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribonucleases P/MRP protein subunit POP1

Names: processing of precursor 1, ribonuclease P/MRP subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

54674327..54687178

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021466787.1 → XP_021322462.1 ribonucleases P/MRP protein subunit POP1

UniProtKB/TrEMBL

A0A8M9NZG1

Conserved Domains (2) summary

pfam06978
Location:58 → 211

POP1; Ribonucleases P/MRP protein subunit POP1

pfam08170
Location:601 → 692

POPLD; POPLD (NUC188) domain