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    trpm1b transient receptor potential cation channel, subfamily M, member 1b [ Danio rerio (zebrafish) ]

    Gene ID: 569946, updated on 11-Apr-2024

    Summary

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    Official Symbol
    trpm1bprovided by ZNC
    Official Full Name
    transient receptor potential cation channel, subfamily M, member 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070424-31
    See related
    Ensembl:ENSDARG00000103476 AllianceGenome:ZFIN:ZDB-GENE-070424-31
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:162329
    Summary
    Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transport into cytosol and cation transmembrane transport. Predicted to act upstream of or within several processes, including G protein-coupled glutamate receptor signaling pathway; cellular response to light stimulus; and protein tetramerization. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in melanoblast; neural crest cell; and retina. Human ortholog(s) of this gene implicated in congenital stationary night blindness and congenital stationary night blindness 1C. Orthologous to human TRPM1 (transient receptor potential cation channel subfamily M member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (34560257..34594542)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (34135445..34153920)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase 7A Neighboring gene Kruppel like factor 13 Neighboring gene transient receptor potential cation channel subfamily M member 1-like Neighboring gene ras and EF-hand domain-containing protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes. Kastenhuber E, et al. Dev Dyn, 2013 Nov. PMID 23908157
    2. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
    3. Pigmentation pathway evolution after whole-genome duplication in fish. Braasch I, et al. Genome Biol Evol, 2009 Nov 25. PMID 20333216, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in metal ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic cation transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transient receptor potential cation channel subfamily M member 1b; transient receptor potential cation channel, subfamily M, member 1b
    Names
    transient receptor potential cation channel, subfamily M, member 1
    transient receptor potential melastatin 1a
    trpm1a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110479.1 → NP_001103949.1  transient receptor potential cation channel subfamily M member 1b

      See identical proteins and their annotated locations for NP_001103949.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133947
      UniProtKB/TrEMBL
      A0A8M1NGM7, A3KNP8
      Related
      ENSDARP00000135392.1, ENSDART00000157519.2
      Conserved Domains (1) summary
      cl19167
      Location:157 → 225
      Bac_export_2; FlhB HrpN YscU SpaS Family

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      34560257..34594542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470522.1 → XP_021326197.1  transient receptor potential cation channel, subfamily M, member 1b isoform X2

      UniProtKB/TrEMBL
      A0A8M9P6H0
      Conserved Domains (1) summary
      cl19167
      Location:270 → 338
      Bac_export_2; FlhB HrpN YscU SpaS Family

    2. XM_021470521.1 → XP_021326196.1  transient receptor potential cation channel, subfamily M, member 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M9PV08
      Conserved Domains (1) summary
      cl19167
      Location:270 → 338
      Bac_export_2; FlhB HrpN YscU SpaS Family
    Nucleotide Protein Strain
    Heading Accession and Version

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