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    rce1b Ras converting CAAX endopeptidase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 566908, updated on 11-Apr-2024

    Summary

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    Official Symbol
    rce1bprovided by ZNC
    Official Full Name
    Ras converting CAAX endopeptidase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-277
    See related
    Ensembl:ENSDARG00000088207 AllianceGenome:ZFIN:ZDB-GENE-091204-277
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-36h11.3
    Summary
    Predicted to enable metalloendopeptidase activity. Predicted to be involved in CAAX-box protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human RCE1 (Ras converting CAAX endopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26495459..26520686, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26455434..26483993, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene zgc:110540 Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene CD248 molecule, endosialin b Neighboring gene adenylosuccinate synthase, like Neighboring gene vascular endothelial growth factor Bb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cd248a and Cd248b in zebrafish participate in innate immune responses. Li X, et al. Front Immunol, 2022. PMID 36119065, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CAAX-box protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within CAAX-box protein processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CAAX prenyl protease 2-like
    Names
    RCE1 homolog, prenyl protein peptidase (S. cerevisiae) b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      26495459..26520686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469090.1 → XP_021324765.1  CAAX prenyl protease 2-like isoform X6

      UniProtKB/TrEMBL
      A0A8M9PUN5
      Conserved Domains (1) summary
      pfam02517
      Location:145 → 232
      Abi; CAAX protease self-immunity

    2. XM_021469089.1 → XP_021324764.1  CAAX prenyl protease 2-like isoform X3

      UniProtKB/TrEMBL
      A0A8M9PIY1
      Conserved Domains (1) summary
      pfam02517
      Location:145 → 246
      Abi; CAAX protease self-immunity

    3. XM_017353000.2 → XP_017208489.1  CAAX prenyl protease 2-like isoform X4

      UniProtKB/TrEMBL
      A0A8M6YUR9

    4. XM_017352998.2 → XP_017208487.1  CAAX prenyl protease 2-like isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z3W7

    5. XM_017353001.2 → XP_017208490.1  CAAX prenyl protease 2-like isoform X5

      UniProtKB/TrEMBL
      A0A8M6Z385

    6. XM_690193.5 → XP_695285.3  CAAX prenyl protease 2-like isoform X2

      UniProtKB/TrEMBL
      A0A8N7UTA9, E9QGI3
      Related
      ENSDARP00000113266.1, ENSDART00000142731.2
      Conserved Domains (2) summary
      COG1266
      Location:58 → 245
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam02517
      Location:144 → 245
      Abi; CAAX protease self-immunity

    7. XM_017353004.2 → XP_017208493.1  CAAX prenyl protease 2-like isoform X8

      UniProtKB/TrEMBL
      A0A8M6YX55

    8. XM_017353003.2 → XP_017208492.1  CAAX prenyl protease 2-like isoform X7

      UniProtKB/TrEMBL
      A0A8M6YVA7

    RNA

    1. XR_001797053.2 RNA Sequence

    2. XR_001797052.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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