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    rhobtb3 Rho related BTB domain containing 3 [ Danio rerio (zebrafish) ]

    Gene ID: 562804, updated on 27-Mar-2024

    Summary

    Official Symbol
    rhobtb3provided by ZNC
    Official Full Name
    Rho related BTB domain containing 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-190
    See related
    Ensembl:ENSDARG00000090036 AllianceGenome:ZFIN:ZDB-GENE-091204-190
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-6b12.5
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Orthologous to human RHOBTB3 (Rho related BTB domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See rhobtb3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (11780883..11820852, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (11688907..11727989, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108180799 Neighboring gene proprotein convertase subtilisin/kexin type 1 Neighboring gene elongation factor for RNA polymerase II 2 Neighboring gene glutaredoxin (thioltransferase) Neighboring gene Rieske (Fe-S) domain containing Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    rho-related BTB domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      11780883..11820852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_686178.9XP_691270.6  rho-related BTB domain-containing protein 3

      UniProtKB/TrEMBL
      A0A8N7TB76, E7EYA0
      Related
      ENSDARP00000109526.2, ENSDART00000126640.3
      Conserved Domains (4) summary
      smart00225
      Location:428518
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:417518
      BTB; BTB/POZ domain
      cl02518
      Location:254296
      BTB; BTB/POZ domain
      cl21455
      Location:97189
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases