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    gnpda2 glucosamine-6-phosphate deaminase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 556291, updated on 27-Mar-2024

    Summary

    Official Symbol
    gnpda2provided by ZNC
    Official Full Name
    glucosamine-6-phosphate deaminase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091117-41
    See related
    Ensembl:ENSDARG00000024443 AllianceGenome:ZFIN:ZDB-GENE-091117-41
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-185e18.2
    Summary
    Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process and amino sugar catabolic process. Predicted to act upstream of or within N-acetylglucosamine metabolic process and carbohydrate metabolic process. Predicted to be active in cytoplasm. Orthologous to several human genes including GNPDA2 (glucosamine-6-phosphate deaminase 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (4276309..4289640)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (4169378..4182721)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 51b Neighboring gene FERM and PDZ domain containing 1b Neighboring gene GTP binding elongation factor GUF1 Neighboring gene gamma-aminobutyric acid receptor subunit alpha-2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glucosamine-6-phosphate deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glucosamine-6-phosphate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within N-acetylglucosamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in N-acetylneuraminate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glucosamine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glucosamine-6-phosphate isomerase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      4276309..4289640
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_679055.7XP_684147.2  glucosamine-6-phosphate isomerase 2

      UniProtKB/TrEMBL
      A0A8N7TCS4, E7F0E2
      Related
      ENSDARP00000039222.6, ENSDART00000038301.8
      Conserved Domains (1) summary
      cl00339
      Location:1253
      SugarP_isomerase; SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ...