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    Clec1a C-type lectin domain family 1, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500337, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Clec1aprovided by RGD
    Official Full Name
    C-type lectin domain family 1, member Aprovided by RGD
    Primary source
    RGD:1566110
    See related
    Ensembl:ENSRNOG00000060460 AllianceGenome:RGD:1566110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566110
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in aspergillosis. Orthologous to human CLEC1A (C-type lectin domain family 1 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 253.8), Heart (RPKM 82.4) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Clec1a in Genome Data Viewer
    Location:
    4q42
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (164561385..164588593, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (162875360..162902571, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163191503..163214678, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 1, member B Neighboring gene C-type lectin domain containing 9A Neighboring gene uncharacterized LOC120102409 Neighboring gene C-type lectin domain containing 7A Neighboring gene oxidized low density lipoprotein receptor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The complete inventory of receptors encoded by the rat natural killer cell gene complex. Flornes LM, et al. Immunogenetics, 2010 Aug. PMID 20544345, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain family 1 member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109253.1 → NP_001102723.1  C-type lectin domain family 1 member A

      See identical proteins and their annotated locations for NP_001102723.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473964
      UniProtKB/TrEMBL
      A6IM48, D3ZGU3
      Related
      ENSRNOP00000069193.1, ENSRNOT00000091602.2
      Conserved Domains (1) summary
      cd03593
      Location:136 → 258
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      164561385..164588593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108218.2 → XP_038964146.1  C-type lectin domain family 1 member A isoform X1

      UniProtKB/TrEMBL
      A6IM48, D3ZGU3
      Conserved Domains (1) summary
      cd03593
      Location:136 → 258
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    2. XM_039108217.2 → XP_038964145.1  C-type lectin domain family 1 member A isoform X1

      UniProtKB/TrEMBL
      A6IM48, D3ZGU3
      Conserved Domains (1) summary
      cd03593
      Location:136 → 258
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    3. XM_039108220.2 → XP_038964148.1  C-type lectin domain family 1 member A isoform X2

      Conserved Domains (1) summary
      cl02432
      Location:136 → 180
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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