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    mlst8 MTOR associated protein, LST8 homolog [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 496930, updated on 5-Mar-2024

    Summary

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    Official Symbol
    mlst8provided by Xenbase
    Official Full Name
    MTOR associated protein, LST8 homologprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-981763
    See related
    Ensembl:ENSXETG00000016102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    gbl; lts8
    Orthologs
    human mouse all
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    Genomic context

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    See mlst8 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (19401086..19414181, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (13551983..13563115, complement)

    Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene BRICHOS domain containing 5 Neighboring gene phosphoglycolate phosphatase Neighboring gene hexosaminidase D like Neighboring gene CASK interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    involved_in TOR signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within TOR signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of TORC1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TORC1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of TORC2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TORC2 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    target of rapamycin complex subunit lst8
    Names
    Protein LTS8 homolog
    TORC subunit lst8
    gable
    protein GbetaL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011443.1 → NP_001011443.1  target of rapamycin complex subunit lst8

      See identical proteins and their annotated locations for NP_001011443.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088512
      UniProtKB/Swiss-Prot
      Q28HP0, Q5I0B4
      UniProtKB/TrEMBL
      A0A6I8R506
      Related
      ENSXETP00000080797.2, ENSXETT00000094222.2
      Conserved Domains (2) summary
      cd00200
      Location:14 → 297
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:47 → 83
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      19401086..19414181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012970370.3 → XP_012825824.1  target of rapamycin complex subunit lst8 isoform X2

      UniProtKB/TrEMBL
      A0A6I8R506, G1K3H6
      Related
      ENSXETP00000035110.4, ENSXETT00000035110.5
      Conserved Domains (2) summary
      cd00200
      Location:15 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:48 → 84
      7WD40; WD40 repeat [structural motif]

    2. XM_031892620.1 → XP_031748480.1  target of rapamycin complex subunit lst8 isoform X1

      UniProtKB/TrEMBL
      A0A6I8R506, G1K3H6
      Conserved Domains (2) summary
      cd00200
      Location:15 → 298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:48 → 84
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5I0B4.1 GenPept UniProtKB/Swiss-Prot:Q5I0B4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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