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    tcn2 transcobalamin 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 496768, updated on 5-Mar-2024

    Summary

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    Official Symbol
    tcn2provided by Xenbase
    Official Full Name
    transcobalamin 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-970701
    See related
    Ensembl:ENSXETG00000019944
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    tc2; d22s676; d22s750
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (166389282..166404328)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (157793871..157809233)

    Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene X-box binding protein 1 Neighboring gene coiled-coil domain containing 117 Neighboring gene purinergic receptor P2X 6 Neighboring gene solute carrier family 35 member E4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cobalamin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cobalamin transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cobalt ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcobalamin-2
    Names
    transcobalamin II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001197106.1 → NP_001184035.1  transcobalamin-2 precursor

      See identical proteins and their annotated locations for NP_001184035.1

      Status: VALIDATED

      Source sequence(s)
      AAMC04000001, BC088039, BC122017
      UniProtKB/TrEMBL
      A9ULJ2, Q5M8G1
      Related
      ENSXETP00000043148.4, ENSXETT00000043148.5
      Conserved Domains (2) summary
      pfam01122
      Location:6 → 322
      Cobalamin_bind; Eukaryotic cobalamin-binding protein
      pfam14478
      Location:354 → 430
      DUF4430; Domain of unknown function (DUF4430)

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      166389282..166404328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012961171.3 → XP_012816625.1  transcobalamin-2 isoform X1

      See identical proteins and their annotated locations for XP_012816625.1

      UniProtKB/TrEMBL
      A9ULJ2, Q5M8G1
      Conserved Domains (2) summary
      pfam01122
      Location:6 → 322
      Cobalamin_bind; Eukaryotic cobalamin-binding protein
      pfam14478
      Location:354 → 430
      DUF4430; Domain of unknown function (DUF4430)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.