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    Mhcl Myosin heavy chain-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41955, updated on 28-Aug-2019

    Summary

    Official Symbol
    Mhclprovided by FlyBase
    Official Full Name
    Myosin heavy chain-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026059
    Locus tag
    Dmel_CG31045
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10218; CG10224; CG31045; Dmel\CG31045; DmPDZ; MHCL(PDZ); Myo7A

    Genomic context

    See Mhcl in Genome Data Viewer
    Location:
    89B2-89B3; 3-58 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16068523..16098761, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11894245..11924483, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mini spindles Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene sex-specific enzyme 2 Neighboring gene Akt1 Neighboring gene Stubble Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT actin-dependent ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT microfilament motor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    myosin complex IEA
    Inferred from Electronic Annotation
    more info
     
    sarcomere IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    myosin heavy chain-like
    Names
    CG31045-PA
    CG31045-PB
    CG31045-PC
    CG31045-PD
    CG31045-PF
    CG31045-PG
    CG31045-PH
    CG31045-PI
    Mhcl-PA
    Mhcl-PB
    Mhcl-PC
    Mhcl-PD
    Mhcl-PF
    Mhcl-PG
    Mhcl-PH
    Mhcl-PI
    Myosin-heavy-chain-like
    PDZ-myosin
    myosin 18
    myosin XVIII
    myosin XVIII (PDZ)
    myosin heavy chain
    NP_001036715.1
    NP_001036716.1
    NP_001189233.1
    NP_001262623.1
    NP_732108.2
    NP_732109.2
    NP_732110.2
    NP_732111.1

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16068523..16098761 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169700.3NP_732108.2  myosin heavy chain-like, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732108.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VEZ0
      Related
      FBpp0082683, FBtr0083229
      Conserved Domains (6) summary
      smart00242
      Location:5561317
      MYSc; Myosin. Large ATPases
      COG1340
      Location:15651833
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd00992
      Location:339426
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01386
      Location:5751305
      MYSc_Myo18; class XVIII myosin, motor domain
      cd16269
      Location:17231734
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:15401750
      GBP_C; Guanylate-binding protein, C-terminal domain
    2. NM_169701.3NP_732109.2  myosin heavy chain-like, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732109.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8INC3
      Related
      FBpp0082685, FBtr0083231
      Conserved Domains (6) summary
      smart00242
      Location:5561317
      MYSc; Myosin. Large ATPases
      COG1340
      Location:15651833
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd00992
      Location:339426
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01386
      Location:5751305
      MYSc_Myo18; class XVIII myosin, motor domain
      cd16269
      Location:17231734
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:15401750
      GBP_C; Guanylate-binding protein, C-terminal domain
    3. NM_001275694.1NP_001262623.1  myosin heavy chain-like, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262623.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGR6
      Related
      FBpp0304712, FBtr0332439
      Conserved Domains (2) summary
      pfam01576
      Location:4061032
      Myosin_tail_1; Myosin tail
      cl19219
      Location:9251033
      DUF342; Protein of unknown function (DUF342)
    4. NM_169703.1NP_732111.1  myosin heavy chain-like, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732111.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8INC1
      Related
      FBpp0082687, FBtr0083233
      Conserved Domains (2) summary
      pfam01576
      Location:4271053
      Myosin_tail_1; Myosin tail
      cl19219
      Location:9461054
      DUF342; Protein of unknown function (DUF342)
    5. NM_001043250.2NP_001036715.1  myosin heavy chain-like, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036715.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KI67
      Related
      FBpp0110274, FBtr0110974
      Conserved Domains (6) summary
      smart00242
      Location:5561317
      MYSc; Myosin. Large ATPases
      COG1340
      Location:15651833
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd00992
      Location:339426
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01386
      Location:5751305
      MYSc_Myo18; class XVIII myosin, motor domain
      cd16269
      Location:17231734
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:15401750
      GBP_C; Guanylate-binding protein, C-terminal domain
    6. NM_001043251.2NP_001036716.1  myosin heavy chain-like, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036716.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KI66
      Related
      FBpp0110273, FBtr0110973
      Conserved Domains (5) summary
      smart00242
      Location:3191080
      MYSc; Myosin. Large ATPases
      COG1340
      Location:13281596
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01386
      Location:3381068
      MYSc_Myo18; class XVIII myosin, motor domain
      cd16269
      Location:14861497
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:13031513
      GBP_C; Guanylate-binding protein, C-terminal domain
    7. NM_170650.4NP_732110.2  myosin heavy chain-like, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732110.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IH49
      Related
      FBpp0082686, FBtr0083232
      Conserved Domains (1) summary
      pfam01576
      Location:153827
      Myosin_tail_1; Myosin tail
    8. NM_001202304.1NP_001189233.1  myosin heavy chain-like, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JCY5
      Related
      FBpp0292853, FBtr0303845
      Conserved Domains (2) summary
      TIGR02168
      Location:7232
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:134446
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
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