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    CG4338 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41849, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG4338provided by FlyBase
    Primary source
    FLYBASE:FBgn0038313
    Locus tag
    Dmel_CG4338
    See related
    AllianceGenome:FB:FBgn0038313
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4338
    Summary
    Predicted to enable transferase activity. Predicted to be involved in maturation of SSU-rRNA. Is expressed in several structures, including anterior endoderm anlage; embryonic/larval midgut; embryonic/larval midgut primordium; embryonic/larval visceral muscle cell; and germ layer. Orthologous to human TSR3 (TSR3 ribosome maturation factor). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    88E11-88E11; 3-56 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15275522..15276474)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11101244..11102196)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ATP synthase, oligomycin sensitivity conferring protein Neighboring gene uncharacterized protein Neighboring gene Zinc/iron regulated transporter-related protein 88E Neighboring gene Centrosomal protein 190kD Neighboring gene antisense RNA:CR46081 Neighboring gene lethal (3) neo43 Neighboring gene MORF-related gene 15 Neighboring gene Tropomyosin 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division. Butcher RD, et al. J Cell Sci, 2004 Mar 1. PMID 14996941
    2. The centrosomal protein CP190 is a component of the gypsy chromatin insulator. Pai CY, et al. Mol Cell, 2004 Dec 3. PMID 15574329
    3. Messenger RNA is a functional component of a chromatin insulator complex. Matzat LH, et al. EMBO Rep, 2013 Oct. PMID 23917615, Free PMC Article
    4. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407
    5. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 18S rRNA aminocarboxypropyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 18S rRNA aminocarboxypropyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4338-PA
    NP_650441.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15275522..15276474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142184.2 → NP_650441.1  uncharacterized protein Dmel_CG4338 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFA0
      Related
      FBpp0082525
      Conserved Domains (3) summary
      COG2042
      Location:69 → 233
      Tsr3; Ribosome biogenesis protein Tsr3 (rRNA maturation) [Translation, ribosomal structure and biogenesis]
      pfam04034
      Location:105 → 229
      DUF367; Domain of unknown function (DUF367)
      pfam04068
      Location:69 → 101
      RLI; Possible Fer4-like domain in RNase L inhibitor, RLI
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFA0 Q9VFA0

    Gene LinkOut

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