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    CG11523 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40458, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG11523provided by FlyBase
    Primary source
    FLYBASE:FBgn0037156
    Locus tag
    Dmel_CG11523
    See related
    AllianceGenome:FB:FBgn0037156
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11523
    Summary
    Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasm. Is expressed in embryonic/larval muscle system; embryonic/larval somatic muscle cell; and organism. Orthologous to human GSKIP (GSK3B interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    79D3-79D3; 3-47 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (22265806..22266679, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (22258906..22259779, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene olf413 Neighboring gene long non-coding RNA:CR45035 Neighboring gene antisense RNA:CR45960 Neighboring gene RIC1 homolog Neighboring gene stable intronic sequence RNA 3 Neighboring gene Dead-box-1 Neighboring gene Serine-arginine protein kinase at 79D Neighboring gene Cysteine string protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Longevity GWAS Using the Drosophila Genetic Reference Panel. Ivanov DK, et al. J Gerontol A Biol Sci Med Sci, 2015 Dec. PMID 25922346, Free PMC Article
    2. Quantitative genomics of aggressive behavior in Drosophila melanogaster. Edwards AC, et al. PLoS Genet, 2006 Sep 15. PMID 17044737, Free PMC Article
    3. An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila. Kockel L, et al. G3 (Bethesda), 2019 Jul 9. PMID 31040111, Free PMC Article
    4. Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED. Hadžić T, et al. Nucleic Acids Res, 2015 Feb 27. PMID 25634895, Free PMC Article
    5. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11523-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      22265806..22266679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141129.3 → NP_649386.1  uncharacterized protein Dmel_CG11523 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649386.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNV2
      Related
      FBpp0078163
      Conserved Domains (1) summary
      pfam05303
      Location:18 → 134
      DUF727; Protein of unknown function (DUF727)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNV2 Q9VNV2

    Gene LinkOut

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