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    rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 394956, updated on 5-Mar-2024

    Summary

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    Official Symbol
    rabgef1provided by Xenbase
    Official Full Name
    RAB guanine nucleotide exchange factor (GEF) 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5952242
    See related
    Ensembl:ENSXETG00000026471
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    rabex5; rabex-5
    Orthologs
    human mouse all
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    Genomic context

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    See rabgef1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (48709259..48733578, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (44387602..44415128, complement)

    Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 75A Neighboring gene transmembrane protein 248 Neighboring gene chemokine (C-C motif) ligand 5 Neighboring gene huntingtin interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC75593

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rab5 GDP/GTP exchange factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204000.1 → NP_989331.1  rab5 GDP/GTP exchange factor

      See identical proteins and their annotated locations for NP_989331.1

      Status: PROVISIONAL

      Source sequence(s)
      BC064156
      UniProtKB/TrEMBL
      A0A6I8PSM3, Q6P377
      Related
      ENSXETP00000055809.3, ENSXETT00000055809.4
      Conserved Domains (1) summary
      pfam01754
      Location:17 → 40
      zf-A20; A20-like zinc finger

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      48709259..48733578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012956676.3 → XP_012812130.2  rab5 GDP/GTP exchange factor isoform X1

      UniProtKB/TrEMBL
      A0A6I8PSG6, A0A6I8Q0I4
      Related
      ENSXETP00000065665.2, ENSXETT00000101542.2
      Conserved Domains (3) summary
      pfam02204
      Location:271 → 371
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      pfam01754
      Location:17 → 39
      zf-A20; A20-like zinc finger
      pfam18151
      Location:159 → 221
      DUF5601; Domain of unknown function (DUF5601)

    2. XM_012956677.3 → XP_012812131.2  rab5 GDP/GTP exchange factor isoform X1

      UniProtKB/TrEMBL
      A0A6I8PSG6, A0A6I8Q0I4
      Conserved Domains (3) summary
      pfam02204
      Location:271 → 371
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      pfam01754
      Location:17 → 39
      zf-A20; A20-like zinc finger
      pfam18151
      Location:159 → 221
      DUF5601; Domain of unknown function (DUF5601)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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