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    CG12822 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35737, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG12822provided by FlyBase
    Primary source
    FLYBASE:FBgn0033229
    Locus tag
    Dmel_CG12822
    See related
    AllianceGenome:FB:FBgn0033229
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12822-PA; Dmel\CG12822
    Summary
    Predicted to enable tRNA (adenine-N6-)-methyltransferase activity. Orthologous to human TRMO (tRNA methyltransferase O). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CG12822 in Genome Data Viewer
    Location:
    43E18-43E18; 2-57 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7832171..7833841)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3719676..3721346)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Proteasome alpha1 subunit Neighboring gene Proteasome alpha1 subunit-related Neighboring gene uncharacterized protein Neighboring gene photorepair Neighboring gene Autophagy-related 10 Neighboring gene Diacyl glycerol kinase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population. Ng'oma E, et al. BMC Genomics, 2020 Jan 28. PMID 31992183, Free PMC Article
    2. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Rogers RL, et al. Mol Biol Evol, 2012 Feb. PMID 21771717, Free PMC Article
    3. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Rogers RL, et al. Genetics, 2009 Jan. PMID 19015547, Free PMC Article
    4. Evolution of alternative splicing in newly evolved genes of Drosophila. Zhan Z, et al. Gene, 2011 Jan 1. PMID 20851753
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12822-PA
    CG12822-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7832171..7833841
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136483.4 → NP_610327.1  uncharacterized protein Dmel_CG12822, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610327.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z759
      Related
      FBpp0087917
      Conserved Domains (1) summary
      pfam01980
      Location:116 → 232
      UPF0066; uncharacterized protein family UPF0066

    2. NM_206052.3 → NP_995774.1  uncharacterized protein Dmel_CG12822, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995774.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MR50
      Conserved Domains (1) summary
      pfam01980
      Location:116 → 232
      UPF0066; uncharacterized protein family UPF0066
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z759 A1Z759
    Q8MR50 Q8MR50

    Gene LinkOut

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