U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CG18478 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34923, updated on 4-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG18478provided by FlyBase
    Primary source
    FLYBASE:FBgn0028517
    Locus tag
    Dmel_CG18478
    See related
    AllianceGenome:FB:FBgn0028517
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS07108.5; Dmel\CG18478; DS07108.5; SPH157; SPH207
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG18478 in Genome Data Viewer
    Location:
    35D3-35D3; 2-51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15670174..15671223)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15670174..15671223)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene stolid Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Drosophila maleless gene counteracts X global aneuploid effects in males. Bhadra U, et al. FEBS J, 2016 Sep. PMID 27456781
    2. The evolutionary analysis of "orphans" from the Drosophila genome identifies rapidly diverging and incorrectly annotated genes. Schmid KJ, et al. Genetics, 2001 Oct. PMID 11606536, Free PMC Article
    3. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
    4. Genie--gene finding in Drosophila melanogaster. Reese MG, et al. Genome Res, 2000 Apr. PMID 10779493, Free PMC Article
    5. Genome-wide gene expression in response to parasitoid attack in Drosophila. Wertheim B, et al. Genome Biol, 2005. PMID 16277749, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG18478-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15670174..15671223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135920.2 → NP_609764.1  uncharacterized protein Dmel_CG18478 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609764.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KT71
      Related
      FBpp0080316
      Conserved Domains (2) summary
      smart00020
      Location:50 → 280
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:50 → 283
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KT71 Q7KT71

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases