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    CG13766 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33922, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG13766provided by FlyBase
    Primary source
    FLYBASE:FBgn0031834
    Locus tag
    Dmel_CG13766
    See related
    AllianceGenome:FB:FBgn0031834
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13766; FBXO16
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    26E3-26E3; 2-21 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6564112..6566181, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6564112..6566181, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cytochrome c oxidase subunit 5B Neighboring gene Cytochrome c oxidase subunit 5B-like Neighboring gene tRNA methyltransferase 6 non-catalytic subunit Neighboring gene Equilibrative nucleoside transporter 2 Neighboring gene Dipeptidyl peptidase 10 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Equilibrative nucleoside transporter 2 regulates associative learning and synaptic function in Drosophila. Knight D, et al. J Neurosci, 2010 Apr 7. PMID 20371825, Free PMC Article
    2. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Barbosa P, et al. J Cell Biol, 2021 Feb 1. PMID 33382409, Free PMC Article
    3. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014
    4. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
    5. Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. Roberts DM, et al. PLoS One, 2012. PMID 22359584, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13766-PA
    CG13766-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6564112..6566181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298752.1 → NP_001285681.1  uncharacterized protein Dmel_CG13766, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285681.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QR4, Q9VMB5
      Conserved Domains (1) summary
      sd00034
      Location:111 → 135
      LRR_AMN1; leucine-rich repeat [structural motif]

    2. NM_135206.3 → NP_609050.1  uncharacterized protein Dmel_CG13766, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609050.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QR4, Q9VMB5
      Related
      FBpp0078959
      Conserved Domains (1) summary
      sd00034
      Location:111 → 135
      LRR_AMN1; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMB5 Q9VMB5

    Gene LinkOut

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