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    CG1529 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33077, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG1529provided by FlyBase
    Primary source
    FLYBASE:FBgn0031144
    Locus tag
    Dmel_CG1529
    See related
    AllianceGenome:FB:FBgn0031144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1529
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval midgut; germ layer; hindgut proper primordium; and presumptive embryonic/larval digestive system. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CG1529 in Genome Data Viewer
    Location:
    19E7-19E7; 1-65 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21028652..21031950, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20899679..20902977, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ryder cup Neighboring gene uncharacterized protein Neighboring gene Nuclear transport factor-2 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44431 Neighboring gene Microsomal glutathione S-transferase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    2. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    3. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407
    4. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article
    5. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1529-PA
    CG1529-PC
    CG1529-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21028652..21031950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144751.2 → NP_001138223.2  uncharacterized protein Dmel_CG1529, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138223.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z152
      Conserved Domains (4) summary
      sd00017
      Location:294 → 315
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:11 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam12756
      Location:201 → 257
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
      pfam15909
      Location:268 → 349
      zf-C2H2_8; C2H2-type zinc ribbon

    2. NM_134577.2 → NP_608421.1  uncharacterized protein Dmel_CG1529, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608421.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRT8, Q9VRD5
      Related
      FBpp0076959
      Conserved Domains (2) summary
      PRK09510
      Location:174 → 278
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      sd00017
      Location:77 → 98
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001298577.1 → NP_001285506.1  uncharacterized protein Dmel_CG1529, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285506.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z152
      Conserved Domains (4) summary
      sd00017
      Location:294 → 315
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:11 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam12756
      Location:201 → 257
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
      pfam15909
      Location:268 → 349
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z152 B7Z152
    Q8MRT8 Q8MRT8
    Q9VRD5 Q9VRD5

    Gene LinkOut

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