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    gspt1l G1 to S phase transition 1, like [ Danio rerio (zebrafish) ]

    Gene ID: 325284, updated on 27-Mar-2024

    Summary

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    Official Symbol
    gspt1lprovided by ZNC
    Official Full Name
    G1 to S phase transition 1, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4009
    See related
    Ensembl:ENSDARG00000098627 AllianceGenome:ZFIN:ZDB-GENE-030131-4009
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gspt1; zehn1143; wu:fa91e05; wu:fc64f03; hm:zehn1143
    Summary
    Predicted to enable GTPase activity and translation release factor activity. Acts upstream of or within vasculature development. Predicted to be part of translation release factor complex. Is expressed in digestive system; head; hindbrain; proliferative region; and somite. Orthologous to human GSPT1 (G1 to S phase transition 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (36646170..36664310)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (36504312..36522452)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-72e1.6 Neighboring gene pyridoxal-dependent decarboxylase domain containing 1 Neighboring gene MPV17 mitochondrial membrane protein like Neighboring gene nudE neurodevelopment protein 1 Neighboring gene myosin, heavy chain 11b, smooth muscle

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Loss of Gspt1l disturbs the patterning of the brain central arteries in zebrafish. Wang H, et al. Biochem Biophys Res Commun, 2017 Apr 22. PMID 28285134
    2. A Systems Biology Approach to the Coordination of Defensive and Offensive Molecular Mechanisms in the Innate and Adaptive Host-Pathogen Interaction Networks. Wu CC, et al. PLoS One, 2016. PMID 26881892, Free PMC Article
    3. Transcriptome analysis of zebrafish embryogenesis using microarrays. Mathavan S, et al. PLoS Genet, 2005 Aug. PMID 16132083, Free PMC Article
    4. Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Ton C, et al. Genome Res, 2000 Dec. PMID 11116087, Free PMC Article
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation release factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of translation release factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G1 to S phase transition 1, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198806.1 → NP_942101.1  G1 to S phase transition 1, like

      See identical proteins and their annotated locations for NP_942101.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053244
      UniProtKB/TrEMBL
      A0A8M1PCQ2, Q7T358
      Related
      ENSDARP00000141332.1, ENSDART00000159948.2
      Conserved Domains (4) summary
      cd01883
      Location:154 → 370
      EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
      COG5256
      Location:150 → 572
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      cd04089
      Location:379 → 460
      eRF3_II; Domain II of the eukaryotic class II release factor
      cd03704
      Location:466 → 572
      eRF3_C_III; C-terminal domain of eRF3

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      36646170..36664310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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