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    NAAT1 Nutrient Amino Acid Transporter 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31457, updated on 4-Apr-2024

    Summary

    Official Symbol
    NAAT1provided by FlyBase
    Official Full Name
    Nutrient Amino Acid Transporter 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0029762
    Locus tag
    Dmel_CG3252
    See related
    AllianceGenome:FB:FBgn0029762
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0149848.3; CG3252; Dmel\CG3252; dmNAT1; DmNAT1; Naat1
    Summary
    Enables amino acid transmembrane transporter activity. Involved in L-amino acid transport; amino acid transport; and sodium ion transport. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in anterior-posterior subdivision of organism; embryonic/larval Malpighian tubule; embryonic/larval digestive system; imaginal disc; and larval ventral nerve cord. Orthologous to human SLC6A7 (solute carrier family 6 member 7) and SLC6A9 (solute carrier family 6 member 9). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    Location:
    4F9-4F9; 1-11 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5405238..5410849, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5299271..5304882, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Calcineurin B Neighboring gene small conductance calcium-activated potassium channel Neighboring gene spoonbill Neighboring gene Ubiquitin specific protease 16/45

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in D-amino acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in L-amino acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in amino acid import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in amino acid transmembrane transport ISM
    Inferred from Sequence Model
    more info
    PubMed 
    involved_in neurotransmitter transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in neutral amino acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sodium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IC
    Inferred by Curator
    more info
    PubMed 

    General protein information

    Preferred Names
    nutrient amino acid transporter 1
    Names
    CG3252-PA
    NAAT1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5405238..5410849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_131991.3NP_572219.1  nutrient amino acid transporter 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572219.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1AK15, Q8MRC8, Q9W4C5
      UniProtKB/TrEMBL
      C7LA87
      Related
      FBpp0070763
      Conserved Domains (1) summary
      cd10324
      Location:40533
      SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain