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    Ptbp2 polypyrimidine tract binding protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310820, updated on 19-Nov-2019

    Summary

    Official Symbol
    Ptbp2provided by RGD
    Official Full Name
    polypyrimidine tract binding protein 2provided by RGD
    Primary source
    RGD:1359267
    See related
    Ensembl:ENSRNOG00000010827
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ptb2; PTBLP; PTBLP-L; PTBLP-S
    Expression
    Biased expression in Brain (RPKM 271.8), Thymus (RPKM 137.1) and 9 other tissues See more
    Orthologs

    Genomic context

    See Ptbp2 in Genome Data Viewer
    Location:
    2q41
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (223261444..223323075, complement)
    106 current Rn_Celera (GCF_000002265.2) 2 AC_000070.1 (200269277..200328535, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (241306857..241368189, complement)

    Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene Ig kappa chain V-V region K2-like Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene uncharacterized LOC108350095 Neighboring gene uncharacterized LOC103691684

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Clone Names

    • MGC95244

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    cerebellum development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    mRNA splice site selection IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA splice site selection ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of RNA splicing ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of neural precursor cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of neural precursor cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spinal cord development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    polypyrimidine tract-binding protein 2
    Names
    PTB-like protein
    neural polypyrimidine tract-binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005555.1NP_001005555.1  polypyrimidine tract-binding protein 2

      See identical proteins and their annotated locations for NP_001005555.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082076
      UniProtKB/Swiss-Prot
      Q66H20
      Related
      ENSRNOP00000015036.6, ENSRNOT00000015036.7
      Conserved Domains (1) summary
      TIGR01649
      Location:57531
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

      Range
      223261444..223323075 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233236.3XP_006233298.1  polypyrimidine tract-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006233298.1

      Conserved Domains (1) summary
      TIGR01649
      Location:57537
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    2. XM_006233238.3XP_006233300.1  polypyrimidine tract-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_006233300.1

      UniProtKB/Swiss-Prot
      Q66H20
      Conserved Domains (1) summary
      TIGR01649
      Location:57532
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    3. XM_006233237.3XP_006233299.1  polypyrimidine tract-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_006233299.1

      Conserved Domains (1) summary
      TIGR01649
      Location:57536
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

    Alternate Rn_Celera

    Genomic

    1. AC_000070.1 Alternate Rn_Celera

      Range
      200269277..200328535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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