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    Smok sperm motility kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290818, updated on 18-Apr-2024

    Summary

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    Official Symbol
    Smokprovided by RGD
    Official Full Name
    sperm motility kinaseprovided by RGD
    Primary source
    RGD:1562638
    See related
    Ensembl:ENSRNOG00000022181 AllianceGenome:RGD:1562638
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562638; RGD1564276
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 470.2) See more
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    Genomic context

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    See Smok in Genome Data Viewer
    Location:
    16q12.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (71160198..71172182)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (64457344..64469296)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (68478513..68597196)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene sperm motility kinase-like Neighboring gene uncharacterized LOC120097503 Neighboring gene sperm motility kinase-like Neighboring gene uncharacterized LOC108353106 Neighboring gene POTE ankyrin domain family, member G

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sperm motility kinase
    NP_001094414.1
    XP_038950323.1
    XP_063131312.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100944.1 → NP_001094414.1  sperm motility kinase

      See identical proteins and their annotated locations for NP_001094414.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128761
      UniProtKB/Swiss-Prot
      A1A5Q6
      UniProtKB/TrEMBL
      A6IVW6
      Related
      ENSRNOP00000033067.5, ENSRNOT00000039592.6
      Conserved Domains (2) summary
      cd14337
      Location:290 → 329
      UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
      cd14003
      Location:23 → 270
      STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      71160198..71172182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039094395.2 → XP_038950323.1  sperm motility kinase isoform X1

      UniProtKB/Swiss-Prot
      A1A5Q6
      UniProtKB/TrEMBL
      A6IVW6
      Conserved Domains (2) summary
      cd14337
      Location:290 → 329
      UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
      cd14003
      Location:23 → 270
      STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

    2. XM_063275242.1 → XP_063131312.1  sperm motility kinase isoform X1

      UniProtKB/Swiss-Prot
      A1A5Q6
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1A5Q6.1 GenPept UniProtKB/Swiss-Prot:A1A5Q6

    Gene LinkOut

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