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    SPBC16G5.05c putative VAP family protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540009, updated on 13-Mar-2024

    Summary

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    Gene symbol
    SPBC16G5.05c
    Gene description
    putative VAP family protein
    Primary source
    PomBase:SPBC16G5.05c
    Locus tag
    SPBC16G5.05c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (4220587..4222612, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene putative ribokinase Neighboring gene 19S proteasome regulatory subunit Rpn12 Neighboring gene putative ubiquitin-protein ligase E3 Neighboring gene putative mitochondrial ribosomal protein subunit L13 Neighboring gene uncharacterized protein Neighboring gene putative prohibitin Neighboring gene miscRNA Neighboring gene putative phosphoribosylanthranilate transferase Trp4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasma Membrane Furrows Control Plasticity of ER-PM Contacts. Ng AQE, et al. Cell Rep, 2020 Feb 4. PMID 32023460
    2. ER-PM Contacts Define Actomyosin Kinetics for Proper Contractile Ring Assembly. Zhang D, et al. Curr Biol, 2016 Mar 7. PMID 26877082, Free PMC Article
    3. A UPR-Induced Soluble ER-Phagy Receptor Acts with VAPs to Confer ER Stress Resistance. Zhao D, et al. Mol Cell, 2020 Sep 17. PMID 32735772
    4. ER-PM Contacts Restrict Exocytic Sites for Polarized Morphogenesis. Ng AYE, et al. Curr Biol, 2018 Jan 8. PMID 29290560
    5. Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture. Zhang D, et al. Curr Biol, 2012 Nov 6. PMID 23041194

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables FFAT motif binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-membrane adaptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum-plasma membrane tethering IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum-plasma membrane tethering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment or maintenance of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of ER location IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in reticulophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cortical endoplasmic reticulum EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum-plasma membrane contact site EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative VAP family protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4220587..4222612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355837.1 → NP_001342726.1  putative VAP family protein [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60119
      Conserved Domains (1) summary
      COG5066
      Location:1 → 292
      SCS2; VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion]
    Nucleotide Protein
    Heading Accession and Version

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