U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ceh-1 Homeobox protein ceh-1 [ Caenorhabditis elegans ]

    Gene ID: 191614, updated on 23-Nov-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    ceh-1
    Gene description
    Homeobox protein ceh-1
    Primary source
    WormBase:WBGene00000428
    Locus tag
    CELE_F16H11.4
    See related
    AllianceGenome:WB:WBGene00000428
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in DVC; lateral ganglion; and seam cell. Orthologous to human NKX1-1 (NK1 homeobox 1) and NKX1-2 (NK1 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ceh-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (4653167..4654157, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Equilibrative nucleoside transporter 1 Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene Major facilitator superfamily domain-containing protein 12

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Homeobox containing genes in the nematode Caenorhabditis elegans. Hawkins NC, et al. Nucleic Acids Res, 1990 Oct 25. PMID 1978282, Free PMC Article
    2. Transgene-mediated co-suppression of DNA topoisomerase-1 gene in Caenorhabditis elegans. Lee MH, et al. Int J Biochem Mol Biol, 2014. PMID 24955284, Free PMC Article
    3. Common logic of transcription factor and microRNA action. Hobert O. Trends Biochem Sci, 2004 Sep. PMID 15337119
    4. Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans. Hukema RK, et al. EMBO J, 2006 Jan 25. PMID 16407969, Free PMC Article
    5. Rapid sequence evolution of transcription factors controlling neuron differentiation in Caenorhabditis. Jovelin R. Mol Biol Evol, 2009 Oct. PMID 19589887, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Homeobox protein ceh-1
    NP_508796.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4653167..4654157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076395.7 → NP_508796.2  Homeobox protein ceh-1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53547
      Conserved Domains (2) summary
      COG5576
      Location:2 → 118
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:44 → 96
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous