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    clpr-1 Calpain catalytic domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189180, updated on 7-Sep-2023

    Summary

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    Gene symbol
    clpr-1
    Gene description
    Calpain catalytic domain-containing protein
    Primary source
    WormBase:WBGene00012233
    Locus tag
    CELE_W04A4.4
    See related
    AllianceGenome:WB:WBGene00012233
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (13676255..13677792, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Leucine Rich repeat-containing domain protein Neighboring gene INTegrator complex Subunit homolog Neighboring gene DUF19 domain-containing protein Neighboring gene CW domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Calpain catalytic domain-containing protein
    NP_001391095.1
    • Partially confirmed by transcript evidence
    NP_493397.3
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      13676255..13677792 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060996.3 → NP_493397.3  Calpain catalytic domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493397.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18165
      Conserved Domains (1) summary
      cl00051
      Location:28 → 229
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.

    2. NM_001404215.1 → NP_001391095.1  Calpain catalytic domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QGE5
    Nucleotide Protein
    Heading Accession and Version

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