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    T23E7.2 Aggrecan core protein;Fibronectin type-III domain-containing protein;Glycosyltransferase;Rab-GAP TBC domain-containing protein;Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 181789, updated on 4-May-2023

    Summary

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    Gene symbol
    T23E7.2
    Gene description
    Aggrecan core protein;Fibronectin type-III domain-containing protein;Glycosyltransferase;Rab-GAP TBC domain-containing protein;Uncharacterized protein
    Primary source
    WormBase:WBGene00020732
    Locus tag
    CELE_T23E7.2
    See related
    AllianceGenome:WB:WBGene00020732
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Orthologous to human FAM186A (family with sequence similarity 186 member A). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    17
    Sequence:
    Chromosome: X; NC_003284.9 (17671027..17680828)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Symporter YagG Neighboring gene Ceramide glucosyltransferase 2 Neighboring gene ncRNA Neighboring gene Telomerase-binding protein EST1A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article
    2. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Aggrecan core protein;Fibronectin type-III domain-containing protein;Glycosyltransferase;Rab-GAP TBC domain-containing protein;Uncharacterized protein
    NP_001360149.1
    • Confirmed by transcript evidence
    NP_001362045.1
    • Confirmed by transcript evidence
    NP_001362054.1
    • Confirmed by transcript evidence
    NP_001362138.1
    • Confirmed by transcript evidence
    NP_001362139.1
    • Confirmed by transcript evidence
    NP_001362140.1
    • Confirmed by transcript evidence
    NP_001362141.1
    • Confirmed by transcript evidence
    NP_001362142.1
    • Confirmed by transcript evidence
    NP_001362143.1
    • Confirmed by transcript evidence
    NP_001370871.1
    • Confirmed by transcript evidence
    NP_510852.2
    • Confirmed by transcript evidence
    NP_510853.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      17671027..17680828
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383705.1 → NP_001370871.1  Uncharacterized protein CELE_T23E7.2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZS5

    2. NM_001373636.3 → NP_001360149.1  Aggrecan core protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MXJ1
      Conserved Domains (2) summary
      PHA03247
      Location:261 → 459
      PHA03247; large tegument protein UL36; Provisional
      PRK14950
      Location:309 → 395
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    3. NM_078451.5 → NP_510852.2  Aggrecan core protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510852.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZS2
      Conserved Domains (1) summary
      pfam10310
      Location:262 → 407
      DUF2413; Protein of unknown function (DUF2413)

    4. NM_001375214.2 → NP_001362045.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZS3
      Conserved Domains (2) summary
      PHA03247
      Location:211 → 409
      PHA03247; large tegument protein UL36; Provisional
      PRK14950
      Location:248 → 345
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    5. NM_001375218.3 → NP_001362054.1  Aggrecan core protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E6J9
      Conserved Domains (2) summary
      PHA03247
      Location:261 → 459
      PHA03247; large tegument protein UL36; Provisional
      PRK14950
      Location:309 → 395
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    6. NM_001375211.2 → NP_001362138.1  Aggrecan core protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4M2N5
      Conserved Domains (2) summary
      PHA03247
      Location:261 → 459
      PHA03247; large tegument protein UL36; Provisional
      PRK14950
      Location:298 → 395
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    7. NM_001375212.2 → NP_001362139.1  Aggrecan core protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4LZC5
      Conserved Domains (2) summary
      PHA03307
      Location:261 → 557
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07003
      Location:261 → 379
      PRK07003; DNA polymerase III subunit gamma/tau

    8. NM_001375213.2 → NP_001362140.1  Aggrecan core protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4LX00
      Conserved Domains (2) summary
      PHA03307
      Location:261 → 557
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07003
      Location:261 → 379
      PRK07003; DNA polymerase III subunit gamma/tau

    9. NM_001375215.2 → NP_001362141.1  Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4LWN1
      Conserved Domains (2) summary
      PHA03247
      Location:211 → 409
      PHA03247; large tegument protein UL36; Provisional
      PRK14950
      Location:259 → 345
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional

    10. NM_001375216.2 → NP_001362142.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4M3L3
      Conserved Domains (3) summary
      PHA03247
      Location:91 → 344
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:211 → 507
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07003
      Location:211 → 329
      PRK07003; DNA polymerase III subunit gamma/tau

    11. NM_001375217.2 → NP_001362143.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5E4LZT0
      Conserved Domains (3) summary
      PHA03247
      Location:91 → 344
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:211 → 507
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07003
      Location:211 → 329
      PRK07003; DNA polymerase III subunit gamma/tau

    12. NM_078452.5 → NP_510853.2  Glycosyltransferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZS4
    Nucleotide Protein
    Heading Accession and Version

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