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    mir-13b-2 mir-13b-2 stem loop [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 12797956, updated on 11-Apr-2024

    Summary

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    Official Symbol
    mir-13b-2provided by FlyBase
    Official Full Name
    mir-13b-2 stem loopprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262421
    Locus tag
    Dmel_CR42972
    See related
    miRBase:MI0000135; AllianceGenome:FB:FBgn0262421
    Gene type
    ncRNA
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    13b-1/2; CR33079; CR42972; dme-mir-13b; dme-miR-13b; Dme-miR-13b; dme-mir-13b-2; dme-miR-13b-2; Dmel\CR42972; miR-13; miR-13-b2; mir-13b; miR-13b; miR-13B; miR-13b-2
    Old locus tag
    Dmel_CR33079
    Summary
    Enables mRNA 3'-UTR binding activity and mRNA binding activity involved in posttranscriptional gene silencing. Involved in gene silencing by miRNA and negative regulation of apoptotic process. Is expressed in embryonic/larval brain; embryonic/larval gut; embryonic/larval somatic muscle cell; and larval ventral nerve cord. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    8C8-8C8; 1-26 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9091230..9091299)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8985263..8985332)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chaperonin containing TCP1 subunit 2 Neighboring gene uncharacterized protein Neighboring gene Bx42

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution and function of the extended miR-2 microRNA family. Marco A, et al. RNA Biol, 2012 Mar. PMID 22336713, Free PMC Article
    2. Novel Triazole linked 2-phenyl benzoxazole derivatives induce apoptosis by inhibiting miR-2, miR-13 and miR-14 function in Drosophila melanogaster. Mondal T, et al. Apoptosis, 2017 Jun. PMID 28401354
    3. microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein. Pinder BD, et al. EMBO Rep, 2013 Jan. PMID 23184089, Free PMC Article
    4. Systematic Curation of miRBase Annotation Using Integrated Small RNA High-Throughput Sequencing Data for C. elegans and Drosophila. Wang X, et al. Front Genet, 2011. PMID 22303321, Free PMC Article
    5. The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Landthaler M, et al. Curr Biol, 2004 Dec 14. PMID 15589161

    See all (64) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • mir-13b-2-RA; Dmel\mir-13b-2-RA; CR42972-RA; Dmel\CR42972-RA
    • mir-13b-2-RB; Dmel\mir-13b-2-RB; CR42972-RB; Dmel\CR42972-RB
    • mir-13b-2-RM; Dmel\mir-13b-2-RM; CR42972-RM; Dmel\CR42972-RM

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in miRNA-mediated post-transcriptional gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RISC complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9091230..9091299
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_047785.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases