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    Gr10a Gustatory receptor 10a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117501, updated on 4-Apr-2024

    Summary

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    Official Symbol
    Gr10aprovided by FlyBase
    Official Full Name
    Gustatory receptor 10aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0045502
    Locus tag
    Dmel_CG32664
    See related
    AllianceGenome:FB:FBgn0045502
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32664; Dmel\CG32664; gr10a; GR10a; Gr10B1
    Summary
    Predicted to enable sweet taste receptor activity. Predicted to be involved in sensory perception of taste. Predicted to be integral component of membrane. Predicted to be active in axon; dendrite; and neuronal cell body. Is expressed in adult olfactory receptor neuron Or10a; gustatory receptor neuron B2 of the terminal organ dorsolateral group; gustatory receptor neuron of terminal organ dorsolateral group; larval gnathal ganglion; and third segment of antenna. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    10B10-10B10; 1-34 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11413467..11417422, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11307500..11309866, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 10b Neighboring gene Odorant receptor 10a Neighboring gene Glutamine synthetase 2 Neighboring gene Ecotropic viral integration site 5 Neighboring gene Sphingosine kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reduced X-linked rare polymorphism in males in comparison to females of Drosophila melanogaster. Takahashi KH, et al. J Hered, 2009 Jan-Feb. PMID 18836147
    2. Two chemosensory receptors together mediate carbon dioxide detection in Drosophila. Jones WD, et al. Nature, 2007 Jan 4. PMID 17167414
    3. Bitter taste receptors confer diverse functions to neurons. Delventhal R, et al. Elife, 2016 Feb 15. PMID 26880560, Free PMC Article
    4. Caffeine Taste Signaling in Drosophila Larvae. Apostolopoulou AA, et al. Front Cell Neurosci, 2016. PMID 27555807, Free PMC Article
    5. High amylose starch consumption induces obesity in Drosophila melanogaster and metformin partially prevents accumulation of storage lipids and shortens lifespan of the insects. Abrat OB, et al. Comp Biochem Physiol A Mol Integr Physiol, 2018 Jan. PMID 29054808

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sweet taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables taste receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of taste NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    gustatory receptor 10a
    Names
    CG32664-PB
    Gr10a-PB
    gustatory receptor 10B1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11413467..11417422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167283.3 → NP_727523.1  gustatory receptor 10a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727523.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1C3K6, P58950
      Related
      FBpp0312371
      Conserved Domains (1) summary
      pfam08395
      Location:20 → 402
      7tm_7; 7tm Chemosensory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P58950.1 P58950

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