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    rgs7b regulator of G protein signaling 7b [ Danio rerio (zebrafish) ]

    Gene ID: 100535325, updated on 11-Apr-2024

    Summary

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    Official Symbol
    rgs7bprovided by ZNC
    Official Full Name
    regulator of G protein signaling 7bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-130531-78
    See related
    Ensembl:ENSDARG00000096687 AllianceGenome:ZFIN:ZDB-GENE-130531-78
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch1073-333p16.1
    Summary
    Predicted to act upstream of or within G protein-coupled receptor signaling pathway; intracellular signal transduction; and negative regulation of signal transduction. Orthologous to human RGS7 (regulator of G protein signaling 7). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (47568077..47631143, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (47570276..47609057, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene formin 2b Neighboring gene gremlin 2, DAN family BMP antagonist b Neighboring gene fumarate hydratase Neighboring gene hematopoietically expressed homeobox

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    regulator of G-protein signaling 7-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      47568077..47631143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480439.1 → XP_021336114.1  regulator of G-protein signaling 7-like

      UniProtKB/TrEMBL
      A0A8M9QEW4
      Related
      ENSDARP00000139503.1, ENSDART00000169548.2
      Conserved Domains (3) summary
      smart00224
      Location:256 → 316
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:326 → 446
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29 → 116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    Nucleotide Protein Strain
    Heading Accession and Version

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    Molecular Biology Databases