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    six4 SIX homeobox 4 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100498150, updated on 8-Mar-2024

    Summary

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    Official Symbol
    six4provided by Xenbase
    Official Full Name
    SIX homeobox 4provided by Xenbase
    Primary source
    Xenbase:XB-GENE-481699
    See related
    Ensembl:ENSXETG00000016941
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    D-Six4
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (102350826..102366223)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (82077571..82093193)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase 5 Neighboring gene MNAT1, CDK activating kinase assembly factor Neighboring gene SIX homeobox 1 Neighboring gene SIX homeobox 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables syntaxin-1 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in SNARE complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    homeobox protein SIX4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      102350826..102366223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031890805.1 → XP_031746665.1  homeobox protein SIX4 isoform X2

      UniProtKB/TrEMBL
      A0A8J1IPI8
      Conserved Domains (2) summary
      cd00086
      Location:270 → 324
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam16878
      Location:150 → 259
      SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

    2. XM_012969236.3 → XP_012824690.1  homeobox protein SIX4 isoform X3

      UniProtKB/TrEMBL
      A0A8J0SX71
      Conserved Domains (2) summary
      cd00086
      Location:270 → 324
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam16878
      Location:150 → 259
      SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

    3. XM_002933735.5 → XP_002933781.2  homeobox protein SIX4 isoform X1

      UniProtKB/TrEMBL
      F6Y0Z9
      Related
      ENSXETP00000036911.4, ENSXETT00000036911.5
      Conserved Domains (2) summary
      cd00086
      Location:270 → 324
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam16878
      Location:150 → 259
      SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain
    Nucleotide Protein Strain
    Heading Accession and Version

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