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    smo smoothened, frizzled class receptor [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100491644, updated on 8-Mar-2024

    Summary

    Official Symbol
    smoprovided by Xenbase
    Official Full Name
    smoothened, frizzled class receptorprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-487420
    See related
    Ensembl:ENSXETG00000014939
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    XSmo; smoothened
    Orthologs
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    Genomic context

    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (87277583..87303653, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (77606768..77632976, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene striatin interacting protein 2 Neighboring gene adenosylhomocysteinase-like 2 Neighboring gene tetraspanin 33 Neighboring gene coiled-coil domain containing 136

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables patched binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in central nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in commissural neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pattern specification process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in smoothened signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane bounded cell projection IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    smoothened homolog
    Names
    X-smoothened
    smoothened, frizzled family receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      87277583..87303653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002931865.5XP_002931911.2  smoothened homolog

      UniProtKB/TrEMBL
      A0A6I8RRT2, A0A6I8RXK0
      Related
      ENSXETP00000083280.2, ENSXETT00000079091.2
      Conserved Domains (2) summary
      cd07451
      Location:39169
      CRD_SMO; Cysteine-rich domain of the smoothened receptor (Smo) integral membrane protein
      cd15030
      Location:193523
      7tmF_SMO_homolog; class F smoothened family membrane region, a homolog of frizzled receptors