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    gphb5 glycoprotein hormone subunit beta 5 [ Danio rerio (zebrafish) ]

    Gene ID: 100310830, updated on 27-Mar-2024

    Summary

    Official Symbol
    gphb5provided by ZNC
    Official Full Name
    glycoprotein hormone subunit beta 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090319-4
    See related
    Ensembl:ENSDARG00000027472 AllianceGenome:ZFIN:ZDB-GENE-090319-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gpb5; si:dkeyp-77c8.7
    Summary
    Predicted to enable hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of thyroid hormone mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Orthologous to human GPHB5 (glycoprotein hormone subunit beta 5). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See gphb5 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (37272970..37289109)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (37147112..37163219)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene estrogen receptor 2b Neighboring gene spectrin repeat containing, nuclear envelope 2b Neighboring gene uncharacterized LOC101885325 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 5b Neighboring gene protein phosphatase 2, regulatory subunit B', epsilon isoform b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of thyroid hormone mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    glycoprotein hormone beta-5
    Names
    glycoprotein hormone beta 5
    thyrostimulin beta subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166338.1NP_001159810.1  glycoprotein hormone beta-5 precursor

      See identical proteins and their annotated locations for NP_001159810.1

      Status: PROVISIONAL

      Source sequence(s)
      BN001273
      UniProtKB/TrEMBL
      C6SUS4, D5FFI4
      Related
      ENSDARP00000031688.6, ENSDART00000035011.8
      Conserved Domains (1) summary
      cd00069
      Location:39132
      GHB_like; Glycoprotein hormone beta chain homologues

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      37272970..37289109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009307450.3XP_009305725.1  glycoprotein hormone beta-5 isoform X1

      See identical proteins and their annotated locations for XP_009305725.1

      UniProtKB/TrEMBL
      C6SUS4, D5FFI4
      Conserved Domains (1) summary
      cd00069
      Location:39132
      GHB_like; Glycoprotein hormone beta chain homologues