ago1 argonaute 1, RISC catalytic component [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: ago1provided by Xenbase
Official Full Name: argonaute 1, RISC catalytic componentprovided by Xenbase
Primary source: Xenbase:XB-GENE-5933499
See related: Ensembl:ENSXETG00000004364
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: eif2c; eif2c1; gerp95
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (81772788..81800671, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (56026255..56059703, complement)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in P-body	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein argonaute-1

Names: argonaute RISC catalytic component 1; eukaryotic translation initiation factor 2C, 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001317215.1 → NP_001304144.1 protein argonaute-1

Status: VALIDATED

Source sequence(s)

AAMC04000002, BC154703, CX894354, CX935992

UniProtKB/TrEMBL

A0A6I8SNS9, F6PSN5

Related

ENSXETP00000009509.5, ENSXETT00000009509.5

Conserved Domains (5) summary

PLN03202
Location:26 → 856

PLN03202; protein argonaute; Provisional

cd02846
Location:225 → 345

PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...

cd04657
Location:390 → 815

Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...

pfam08699
Location:175 → 224

ArgoL1; Argonaute linker 1 domain

pfam16486
Location:26 → 164

ArgoN; N-terminal domain of argonaute