atp7a ATPase copper transporting alpha [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: atp7aprovided by Xenbase
Official Full Name: ATPase copper transporting alphaprovided by Xenbase
Primary source: Xenbase:XB-GENE-1010489
See related: Ensembl:ENSXETG00000033355
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: kal
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (45747786..45793296)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (24566908..24611880)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables P-type monovalent copper transporter activity	IEA Inferred from Electronic Annotation more info
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within copper ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within copper ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic cation transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in trans-Golgi network	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: copper-transporting ATPase 1

Names: ATPase, Cu++ transporting, alpha polypeptide; kaleidoscope

NP_001361526.1

EC 7.2.2.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001374597.1 → NP_001361526.1 copper-transporting ATPase 1

Status: VALIDATED

Source sequence(s)

AAMC03031022

UniProtKB/TrEMBL

A0A6I8QF43

Related

ENSXETP00000071019.1, ENSXETT00000093959.2

Conserved Domains (2) summary

cd00371
Location:384 → 447

HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...

cd02094
Location:657 → 1389

P-type_ATPase_Cu-like; P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

45747786..45793296

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001130265.1: Suppressed sequence

Description

NM_001130265.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.