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    tcf7l2 transcription factor 7 like 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100101719, updated on 8-Mar-2024

    Summary

    Official Symbol
    tcf7l2provided by Xenbase
    Official Full Name
    transcription factor 7 like 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-485975
    See related
    Ensembl:ENSXETG00000018735
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    tcf4; tcf4e; XTCF-4
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See tcf7l2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (3162581..3320606, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683413.1 (294594..459789, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116412197 Neighboring gene hyaluronan binding protein 2 Neighboring gene vesicle transport through interaction with t-SNAREs 1A Neighboring gene zinc finger DHHC-type containing 6

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transcription factor 7-like 2
    Names
    T-cell factor 4
    transcription factor 7-like 2 (T-cell specific, HMG-box)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001244993.2NP_001231922.1  transcription factor 7-like 2

      Status: VALIDATED

      Source sequence(s)
      BC136073, BQ525264, CX972925, DR831732
      UniProtKB/TrEMBL
      A0A803J833, A0A803KCZ9
      Related
      ENSXETP00000118284.1, ENSXETT00000111689.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      3162581..3320606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031904729.1XP_031760589.1  transcription factor 7-like 2 isoform X27

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRS7
      Related
      ENSXETP00000104016.1, ENSXETT00000109355.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    2. XM_031904703.1XP_031760563.1  transcription factor 7-like 2 isoform X3

      UniProtKB/TrEMBL
      A0A8J1JRN9, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:350417
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    3. XM_031904713.1XP_031760573.1  transcription factor 7-like 2 isoform X12

      UniProtKB/TrEMBL
      A0A8J1JRP8, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:349416
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    4. XM_031904704.1XP_031760564.1  transcription factor 7-like 2 isoform X4

      UniProtKB/TrEMBL
      A0A8J1JRQ3, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:349416
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    5. XM_031904707.1XP_031760567.1  transcription factor 7-like 2 isoform X7

      UniProtKB/TrEMBL
      A0A8J1JRP1, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    6. XM_031904706.1XP_031760566.1  transcription factor 7-like 2 isoform X6

      UniProtKB/TrEMBL
      A0A8J1JVF5, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    7. XM_031904715.1XP_031760575.1  transcription factor 7-like 2 isoform X14

      UniProtKB/TrEMBL
      A0A8J1JU61, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:326393
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    8. XM_031904718.1XP_031760578.1  transcription factor 7-like 2 isoform X17

      UniProtKB/TrEMBL
      A0A8J1JRQ2, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:330397
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    9. XM_031904705.1XP_031760565.1  transcription factor 7-like 2 isoform X5

      UniProtKB/TrEMBL
      A0A8J1JU51, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:349416
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    10. XM_031904711.1XP_031760571.1  transcription factor 7-like 2 isoform X10

      UniProtKB/TrEMBL
      A0A803JJW7, F7BVL1
      Related
      ENSXETP00000108237.1, ENSXETT00000106354.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    11. XM_031904710.1XP_031760570.1  transcription factor 7-like 2 isoform X9

      UniProtKB/TrEMBL
      A0A803JGE8, F7BVL1
      Related
      ENSXETP00000106957.1, ENSXETT00000120383.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    12. XM_031904701.1XP_031760561.1  transcription factor 7-like 2 isoform X1

      UniProtKB/TrEMBL
      A0A8J1JVF1, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    13. XM_031904717.1XP_031760577.1  transcription factor 7-like 2 isoform X16

      UniProtKB/TrEMBL
      A0A8J1JRQ0, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:330397
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    14. XM_031904714.1XP_031760574.1  transcription factor 7-like 2 isoform X13

      UniProtKB/TrEMBL
      A0A8J1JRR3, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:330397
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    15. XM_031904716.1XP_031760576.1  transcription factor 7-like 2 isoform X15

      UniProtKB/TrEMBL
      A0A8J1JVG4, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:335402
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    16. XM_031904709.1XP_031760569.1  transcription factor 7-like 2 isoform X8

      UniProtKB/TrEMBL
      A0A8J1JRQ7, F7BVL1
      Conserved Domains (2) summary
      cd01388
      Location:335402
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    17. XM_031904702.1XP_031760562.1  transcription factor 7-like 2 isoform X2

      UniProtKB/TrEMBL
      A0A803JZB0, F7BVL1
      Related
      ENSXETP00000113375.1, ENSXETT00000117277.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    18. XM_031904712.1XP_031760572.1  transcription factor 7-like 2 isoform X11

      UniProtKB/TrEMBL
      A0A803J969, F7BVL1
      Related
      ENSXETP00000104407.1, ENSXETT00000124488.1
      Conserved Domains (2) summary
      cd01388
      Location:335402
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    19. XM_031904722.1XP_031760582.1  transcription factor 7-like 2 isoform X21

      UniProtKB/TrEMBL
      A0A1B8Y735, A0A8J1JRQ5
      Conserved Domains (2) summary
      cd01388
      Location:210277
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:42116
      CTNNB1_binding; N-terminal CTNNB1 binding
    20. XM_031904725.1XP_031760585.1  transcription factor 7-like 2 isoform X23

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JU71
      Conserved Domains (2) summary
      cd01388
      Location:345412
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    21. XM_031904733.1XP_031760593.1  transcription factor 7-like 2 isoform X31

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRR6
      Conserved Domains (2) summary
      cd01388
      Location:326393
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    22. XM_031904724.1XP_031760584.1  transcription factor 7-like 2 isoform X22

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRS3
      Conserved Domains (2) summary
      cd01388
      Location:349416
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    23. XM_031904732.1XP_031760592.1  transcription factor 7-like 2 isoform X30

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRR2
      Conserved Domains (2) summary
      cd01388
      Location:330397
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    24. XM_031904731.1XP_031760591.1  transcription factor 7-like 2 isoform X29

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JVH9
      Conserved Domains (2) summary
      cd01388
      Location:335402
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    25. XM_031904736.1XP_031760596.1  transcription factor 7-like 2 isoform X34

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JVI3
      Conserved Domains (2) summary
      cd01388
      Location:326393
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    26. XM_031904728.1XP_031760588.1  transcription factor 7-like 2 isoform X26

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRR1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    27. XM_031904721.1XP_031760581.1  transcription factor 7-like 2 isoform X20

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JVG9
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    28. XM_031904735.1XP_031760595.1  transcription factor 7-like 2 isoform X33

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JU79
      Conserved Domains (2) summary
      cd01388
      Location:330397
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    29. XM_031904730.1XP_031760590.1  transcription factor 7-like 2 isoform X28

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JU75
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    30. XM_031904734.1XP_031760594.1  transcription factor 7-like 2 isoform X32

      UniProtKB/TrEMBL
      A0A803J833, A0A8J1JRT2
      Conserved Domains (2) summary
      cd01388
      Location:335402
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17236
      CTNNB1_binding; N-terminal CTNNB1 binding
    31. XM_031904727.1XP_031760587.1  transcription factor 7-like 2 isoform X25

      UniProtKB/TrEMBL
      A0A803K7L6, A0A8J1JRQ9
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    32. XM_031904726.1XP_031760586.1  transcription factor 7-like 2 isoform X24

      UniProtKB/TrEMBL
      A0A803K7L6, A0A8J1JVH4
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    33. XM_031904719.1XP_031760579.1  transcription factor 7-like 2 isoform X18

      UniProtKB/TrEMBL
      A0A803K7L6, A0A8J1JRR8
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding
    34. XM_031904720.1XP_031760580.1  transcription factor 7-like 2 isoform X19

      UniProtKB/TrEMBL
      A0A803K7L6, A0A803KC73
      Related
      ENSXETP00000117986.1, ENSXETT00000110053.1
      Conserved Domains (2) summary
      cd01388
      Location:354421
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:17255
      CTNNB1_binding; N-terminal CTNNB1 binding

    RNA

    1. XR_004223447.1 RNA Sequence