cers2 ceramide synthase 2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: cers2provided by Xenbase
Official Full Name: ceramide synthase 2provided by Xenbase
Primary source: Xenbase:XB-GENE-852703
See related: Ensembl:ENSXETG00000038346
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: lass2; sp260; tmsg1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (126696479..126721543, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (106069064..106094014, complement)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables sphingosine N-acyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axis elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within ceramide biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within gastrulation with mouth forming second	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sphingolipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ceramide synthase 2

Names: LAG1 homolog, ceramide synthase 2

NP_001090742.1

EC 2.3.1.24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001097273.1 → NP_001090742.1 ceramide synthase 2

See identical proteins and their annotated locations for NP_001090742.1

Status: PROVISIONAL

Source sequence(s)

BC129021

UniProtKB/TrEMBL

A0A6I8RAN8, A1L1E5, F6XWC3

Related

ENSXETP00000019577.3, ENSXETT00000019577.5

Conserved Domains (2) summary

smart00724
Location:131 → 332

TLC; TRAM, LAG1 and CLN8 homology domains

cd00086
Location:84 → 128

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.