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    Brinp2 bone morphogenic protein/retinoic acid inducible neural-specific 2 [ Mus musculus (house mouse) ]

    Gene ID: 240843, updated on 23-May-2018
    Official Symbol
    Brinp2provided by MGI
    Official Full Name
    bone morphogenic protein/retinoic acid inducible neural-specific 2provided by MGI
    Primary source
    MGI:MGI:2443333
    See related
    Ensembl:ENSMUSG00000004031 Vega:OTTMUSG00000049880
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam5b; BB361039; mKIAA1747; 6430517E21Rik
    Expression
    Biased expression in frontal lobe adult (RPKM 16.1), cortex adult (RPKM 14.4) and 7 other tissues See more
    Orthologs
    See Brinp2 in Genome Data Viewer
    Location:
    1; 1 H1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (158245265..158356528, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (160175400..160286391, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34423 Neighboring gene predicted gene, 39686 Neighboring gene astrotactin 1 Neighboring gene microRNA 488 Neighboring gene pappalysin 2

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle arrest IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to retinoic acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to retinoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of mitotic cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of neuron differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    BMP/retinoic acid-inducible neural-specific protein 2
    Names
    family with sequence similarity 5, member B
    protein FAM5B

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207583.2NP_997466.2  BMP/retinoic acid-inducible neural-specific protein 2 precursor

      See identical proteins and their annotated locations for NP_997466.2

      Status: VALIDATED

      Source sequence(s)
      BC076572, CO043107
      Consensus CDS
      CCDS15401.1
      UniProtKB/Swiss-Prot
      Q6DFY8
      Related
      ENSMUSP00000004133.8, OTTMUSP00000068631, ENSMUST00000004133.10, OTTMUST00000127006
      Conserved Domains (1) summary
      smart00457
      Location:90281
      MACPF; membrane-attack complex / perforin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      158245265..158356528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496837.1XP_006496900.1  BMP/retinoic acid-inducible neural-specific protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006496900.1

      UniProtKB/Swiss-Prot
      Q6DFY8
      Conserved Domains (1) summary
      smart00457
      Location:90281
      MACPF; membrane-attack complex / perforin
    2. XM_006496836.1XP_006496899.1  BMP/retinoic acid-inducible neural-specific protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006496899.1

      UniProtKB/Swiss-Prot
      Q6DFY8
      Conserved Domains (1) summary
      smart00457
      Location:90281
      MACPF; membrane-attack complex / perforin
    3. XM_011238810.1XP_011237112.1  BMP/retinoic acid-inducible neural-specific protein 2 isoform X2

      Conserved Domains (1) summary
      pfam04579
      Location:136167
      Keratin_matx; Keratin, high-sulphur matrix protein
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