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    Dcun1d3 DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 233805, updated on 12-Aug-2018

    Summary

    Official Symbol
    Dcun1d3provided by MGI
    Official Full Name
    DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:2679003
    See related
    Ensembl:ENSMUSG00000048787 Vega:OTTMUSG00000025619
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BC030335; 1700020A13Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 6.8), bladder adult (RPKM 2.7) and 26 other tissues See more
    Orthologs

    Genomic context

    See Dcun1d3 in Genome Data Viewer
    Location:
    7; 7 F2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (119853158..119896169, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (126996677..127039259, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene UPF0124 protein C13orf31 homolog Neighboring gene acyl-CoA synthetase medium-chain family member 3 Neighboring gene exoribonuclease 2 Neighboring gene RNA exonuclease 5 Neighboring gene LYR motif containing 1 Neighboring gene dynein, axonemal, heavy chain 3 Neighboring gene predicted gene, 40455 Neighboring gene ribosomal protein S9 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40975

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cullin family protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-like protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein neddylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to UV-C ISO
    Inferred from Sequence Orthology
    more info
     
    response to gamma radiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    DCN1-like protein 3
    Names
    DCUN1 domain-containing protein 3
    defective in cullin neddylation protein 1-like protein 3
    NP_001157175.1
    NP_775584.1
    XP_006507744.1
    XP_011240050.1
    XP_011240051.1
    XP_011240052.1
    XP_011240053.1
    XP_017177689.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163703.1NP_001157175.1  DCN1-like protein 3

      See identical proteins and their annotated locations for NP_001157175.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC122423, AC131702
      Consensus CDS
      CCDS21789.1
      UniProtKB/Swiss-Prot
      Q8K0V2
      Related
      ENSMUSP00000058968.6, OTTMUSP00000031132, ENSMUST00000059851.13, OTTMUST00000063023
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    2. NM_173408.3NP_775584.1  DCN1-like protein 3

      See identical proteins and their annotated locations for NP_775584.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC122423, AC131702
      Consensus CDS
      CCDS21789.1
      UniProtKB/Swiss-Prot
      Q8K0V2
      Related
      ENSMUSP00000095686.2, OTTMUSP00000031134, ENSMUST00000098080.8, OTTMUST00000063025
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      119853158..119896169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241751.1XP_011240053.1  DCN1-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011240053.1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    2. XM_011241750.2XP_011240052.1  DCN1-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011240052.1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    3. XM_006507681.2XP_006507744.1  DCN1-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006507744.1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    4. XM_011241749.1XP_011240051.1  DCN1-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011240051.1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Related
      ENSMUSP00000102129.1, OTTMUSP00000031133, ENSMUST00000106519.7, OTTMUST00000063024
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    5. XM_011241748.2XP_011240050.1  DCN1-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011240050.1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
    6. XM_017322200.1XP_017177689.1  DCN1-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q8K0V2
      Conserved Domains (1) summary
      pfam03556
      Location:161276
      Cullin_binding; Cullin binding
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