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    Abhd17a abhydrolase domain containing 17A [ Mus musculus (house mouse) ]

    Gene ID: 216169, updated on 9-Sep-2018

    Summary

    Official Symbol
    Abhd17aprovided by MGI
    Official Full Name
    abhydrolase domain containing 17Aprovided by MGI
    Primary source
    MGI:MGI:106388
    See related
    Ensembl:ENSMUSG00000003346 Vega:OTTMUSG00000047019
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam108a; BC005632; D10Bwg1364e; 1700013O15Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 251.7), adrenal adult (RPKM 194.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Abhd17a in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (80583649..80590341, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80046394..80053086, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene REX1, RNA exonuclease 1 Neighboring gene predicted gene, 31057 Neighboring gene Kruppel-like factor 16 Neighboring gene predicted gene, 26710 Neighboring gene secretory carrier membrane protein 4 Neighboring gene adenosine deaminase, tRNA-specific 3 Neighboring gene microRNA 6912

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC11699, MGC90979

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    palmitoyl-(protein) hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of protein localization to microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to endosome ISO
    Inferred from Sequence Orthology
    more info
     
    protein depalmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of postsynapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    anchored component of postsynaptic density membrane ISO
    Inferred from Sequence Orthology
    more info
     
    anchored component of postsynaptic recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    alpha/beta hydrolase domain-containing protein 17A; protein ABHD17A
    Names
    abhydrolase domain-containing protein 17A
    abhydrolase domain-containing protein FAM108A
    family with sequence similarity 108, member A
    mFLJ00358 protein
    NP_663396.1
    XP_006513567.1
    XP_017169383.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145421.2NP_663396.1  alpha/beta hydrolase domain-containing protein 17A

      See identical proteins and their annotated locations for NP_663396.1

      Status: VALIDATED

      Source sequence(s)
      AC152058
      Consensus CDS
      CCDS24027.1
      UniProtKB/Swiss-Prot
      Q99JW1
      Related
      ENSMUSP00000003436.5, OTTMUSP00000067004, ENSMUST00000003436.11, OTTMUST00000121789
      Conserved Domains (1) summary
      COG1073
      Location:113305
      FrsA; Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      80583649..80590341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513504.2XP_006513567.1  protein ABHD17A isoform X2

      Conserved Domains (2) summary
      COG1073
      Location:117240
      FrsA; Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family [Signal transduction mechanisms]
      pfam12695
      Location:110220
      Abhydrolase_5; Alpha/beta hydrolase family
    2. XM_017313894.1XP_017169383.1  protein ABHD17A isoform X1

      UniProtKB/Swiss-Prot
      Q99JW1
      Conserved Domains (1) summary
      COG1073
      Location:113305
      FrsA; Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family [Signal transduction mechanisms]
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