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    Susd4 sushi domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 96935, updated on 31-Jan-2019

    Summary

    Official Symbol
    Susd4provided by MGI
    Official Full Name
    sushi domain containing 4provided by MGI
    Primary source
    MGI:MGI:2138351
    See related
    Ensembl:ENSMUSG00000038576
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    N28096; AI848994; E430021N18Rik
    Expression
    Biased expression in frontal lobe adult (RPKM 29.8), cortex adult (RPKM 26.8) and 13 other tissues See more
    Orthologs

    Genomic context

    See Susd4 in Genome Data Viewer
    Location:
    1; 1 H5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (182763910..182896596)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (184695037..184825785)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene calpain 8 Neighboring gene coiled-coil domain containing 185 Neighboring gene toll-like receptor 5 Neighboring gene predicted gene, 33747

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC30368

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    negative regulation of complement activation, alternative pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of complement activation, classical pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of complement activation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sushi domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356461.1NP_001343390.1  sushi domain-containing protein 4 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151579, AC170917
      Conserved Domains (2) summary
      smart00032
      Location:243297
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    2. NM_001356462.1NP_001343391.1  sushi domain-containing protein 4 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151579, AC170917
      Conserved Domains (2) summary
      smart00032
      Location:243297
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    3. NM_001356463.1NP_001343392.1  sushi domain-containing protein 4 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151579, AC170917
      Conserved Domains (2) summary
      smart00032
      Location:245299
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    4. NM_001356464.1NP_001343393.1  sushi domain-containing protein 4 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151579, AC170917
      Conserved Domains (2) summary
      smart00032
      Location:245299
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    5. NM_144796.5NP_659045.2  sushi domain-containing protein 4 isoform 1 precursor

      See identical proteins and their annotated locations for NP_659045.2

      Status: VALIDATED

      Source sequence(s)
      AC151579, AC170917
      Consensus CDS
      CCDS15590.1
      UniProtKB/Swiss-Prot
      Q8BH32
      Related
      ENSMUSP00000082873.3, ENSMUST00000085724.4
      Conserved Domains (2) summary
      smart00032
      Location:243297
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      182763910..182896596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006497061.3XP_006497124.1  sushi domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q8BH32
      Conserved Domains (2) summary
      smart00032
      Location:245299
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    2. XM_006497064.3XP_006497127.1  sushi domain-containing protein 4 isoform X2

      UniProtKB/Swiss-Prot
      Q8BH32
      Related
      ENSMUSP00000119488.1, ENSMUST00000153348.7
      Conserved Domains (2) summary
      smart00032
      Location:243297
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    3. XM_006497063.1XP_006497126.1  sushi domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006497126.1

      UniProtKB/Swiss-Prot
      Q8BH32
      Conserved Domains (2) summary
      smart00032
      Location:245299
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cl27761
      Location:57238
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
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