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    Lancl1 LanC (bacterial lantibiotic synthetase component C)-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 14768, updated on 12-Aug-2018

    Summary

    Official Symbol
    Lancl1provided by MGI
    Official Full Name
    LanC (bacterial lantibiotic synthetase component C)-like 1provided by MGI
    Primary source
    MGI:MGI:1336997
    See related
    Ensembl:ENSMUSG00000026000 Vega:OTTMUSG00000021584
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p40; Gpr69; Gpr69a; AW124738
    Expression
    Broad expression in testis adult (RPKM 84.4), cortex adult (RPKM 23.2) and 20 other tissues See more
    Orthologs

    Genomic context

    See Lancl1 in Genome Data Viewer
    Location:
    1; 1 C3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (67000517..67038889, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (67047091..67085439, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31, pseudogene 14 Neighboring gene histidyl-tRNA synthetase pseudogene Neighboring gene carbamoyl-phosphate synthetase 1 Neighboring gene predicted gene, 39658

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    glutathione binding ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle receptor binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    lanC-like protein 1
    Names
    40 kDa erythrocyte membrane protein
    G protein-coupled receptor 69
    G protein-coupled receptor 69A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190984.1NP_001177913.1  lanC-like protein 1

      See identical proteins and their annotated locations for NP_001177913.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC133187, BC058560
      Consensus CDS
      CCDS15025.1
      UniProtKB/Swiss-Prot
      O89112
      Related
      ENSMUSP00000113080.1, OTTMUSP00000032757, ENSMUST00000119559.7, OTTMUST00000065662
      Conserved Domains (2) summary
      cd04794
      Location:62395
      euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein
      cl04955
      Location:189
      LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
    2. NM_001190985.1NP_001177914.1  lanC-like protein 1

      See identical proteins and their annotated locations for NP_001177914.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC133187
      Consensus CDS
      CCDS15025.1
      UniProtKB/Swiss-Prot
      O89112
      Related
      ENSMUSP00000109612.3, OTTMUSP00000024066, ENSMUST00000113979.9, OTTMUST00000051237
      Conserved Domains (2) summary
      cd04794
      Location:62395
      euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein
      cl04955
      Location:189
      LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
    3. NM_021295.3NP_067270.1  lanC-like protein 1

      See identical proteins and their annotated locations for NP_067270.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC133187, Y11550
      Consensus CDS
      CCDS15025.1
      UniProtKB/Swiss-Prot
      O89112
      Related
      ENSMUSP00000027149.5, OTTMUSP00000024065, ENSMUST00000027149.11, OTTMUST00000051236
      Conserved Domains (2) summary
      cd04794
      Location:62395
      euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein
      cl04955
      Location:189
      LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      67000517..67038889 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011238435.2XP_011236737.1  lanC-like protein 1 isoform X1

      Conserved Domains (1) summary
      cd04794
      Location:16349
      euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187020.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      1415046..1453478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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