Format

Send to:

Choose Destination
    • Showing Current items.

    Btg2 B cell translocation gene 2, anti-proliferative [ Mus musculus (house mouse) ]

    Gene ID: 12227, updated on 8-Dec-2018

    Summary

    Official Symbol
    Btg2provided by MGI
    Official Full Name
    B cell translocation gene 2, anti-proliferativeprovided by MGI
    Primary source
    MGI:MGI:108384
    See related
    Ensembl:ENSMUSG00000020423
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pc3; APRO1; TIS21; AA959598
    Expression
    Broad expression in thymus adult (RPKM 131.1), spleen adult (RPKM 49.4) and 21 other tissues See more
    Orthologs

    Genomic context

    See Btg2 in Genome Data Viewer
    Location:
    1 E4; 1 58.1 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (134074865..134079155, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (135971442..135975732, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene fibromodulin Neighboring gene uncharacterized LOC105246710 Neighboring gene predicted gene, 31974 Neighboring gene predicted gene, 32039

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    anterior/posterior pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    associative learning IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    central nervous system neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dentate gyrus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of neural precursor cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ISO
    Inferred from Sequence Orthology
    more info
     
    protein methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    protein BTG2
    Names
    BTG family member 2
    NGF-inducible protein TIS21

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007570.2NP_031596.1  protein BTG2

      See identical proteins and their annotated locations for NP_031596.1

      Status: VALIDATED

      Source sequence(s)
      AK133796, AK171400, BQ561887, BY766758
      Consensus CDS
      CCDS15302.1
      UniProtKB/Swiss-Prot
      Q04211
      UniProtKB/TrEMBL
      Q3TF68
      Related
      ENSMUSP00000020692.6, ENSMUST00000020692.6
      Conserved Domains (1) summary
      pfam07742
      Location:9122
      BTG; BTG family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      134074865..134079155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center