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    Adss adenylosuccinate synthetase, non muscle [ Mus musculus (house mouse) ]

    Gene ID: 11566, updated on 23-May-2018

    Summary

    Official Symbol
    Adssprovided by MGI
    Official Full Name
    adenylosuccinate synthetase, non muscleprovided by MGI
    Primary source
    MGI:MGI:87948
    See related
    Ensembl:ENSMUSG00000015961 Vega:OTTMUSG00000034836
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AS; Adss2; AI314886
    Expression
    Ubiquitous expression in CNS E18 (RPKM 16.5), CNS E14 (RPKM 15.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Adss in Genome Data Viewer
    Location:
    1; 1 H4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (177763176..177796695, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (179693309..179726640, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2310043L19 gene Neighboring gene RIKEN cDNA 1700016C15 gene Neighboring gene predicted gene, 30115 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene cation channel sperm associated auxiliary subunit epsilon 1 Neighboring gene catsper channel auxiliary subunit epsilon 2 Neighboring gene translin-associated factor X pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    adenylosuccinate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    adenylosuccinate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    adenylosuccinate synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    'de novo' AMP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    AMP biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    AMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    IMP metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    IMP metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    aspartate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    purine nucleotide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    adenylosuccinate synthetase isozyme 2
    Names
    AMPSase 2
    IMP--aspartate ligase 2
    L-type adenylosuccinate synthetase
    adSS 2
    adenylosuccinate synthetase 2, non muscle
    adenylosuccinate synthetase, acidic isozyme
    adenylosuccinate synthetase, liver isozyme
    adenylosuccinate synthetase, non-muscle isozyme
    NP_031448.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007422.3NP_031448.2  adenylosuccinate synthetase isozyme 2

      See identical proteins and their annotated locations for NP_031448.2

      Status: VALIDATED

      Source sequence(s)
      AK028060
      Consensus CDS
      CCDS15555.1
      UniProtKB/Swiss-Prot
      P46664
      UniProtKB/TrEMBL
      B9EIE9
      Related
      ENSMUSP00000016105.8, OTTMUSP00000048261, ENSMUST00000016105.8, OTTMUST00000088544
      Conserved Domains (1) summary
      pfam00709
      Location:32453
      Adenylsucc_synt; Adenylosuccinate synthetase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      177763176..177796695 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001785476.1 RNA Sequence

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