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    Dnm1l dynamin 1-like [ Mus musculus (house mouse) ]

    Gene ID: 74006, updated on 25-Sep-2018

    Summary

    Official Symbol
    Dnm1lprovided by MGI
    Official Full Name
    dynamin 1-likeprovided by MGI
    Primary source
    MGI:MGI:1921256
    See related
    Ensembl:ENSMUSG00000022789
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dlp1; Drp1; Dnmlp1; python; AI450666; 6330417M19Rik
    Summary
    This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Feb 2013]
    Expression
    Broad expression in cerebellum adult (RPKM 25.5), CNS E18 (RPKM 24.8) and 24 other tissues See more
    Orthologs

    Genomic context

    See Dnm1l in Genome Data Viewer
    Location:
    16; 16 A2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (16312228..16359044, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (16312326..16359123, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L30 pseudogene Neighboring gene tyrosyl-tRNA synthetase 2 (mitochondrial) Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein L pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Apoptosis, organism-specific biosystem (from REACTOME)
      Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Apoptotic execution phase, organism-specific biosystem (from REACTOME)
      Apoptotic execution phase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • NOD-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      NOD-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • NOD-like receptor signaling pathway, conserved biosystem (from KEGG)
      NOD-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • Programmed Cell Death, organism-specific biosystem (from REACTOME)
      Programmed Cell Death, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • TNF signaling pathway, organism-specific biosystem (from KEGG)
      TNF signaling pathway, organism-specific biosystemTumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal pathways including apoptosis and cell survival as well as inflammation and immunity. Activated TNF...
    • TNF signaling pathway, conserved biosystem (from KEGG)
      TNF signaling pathway, conserved biosystemTumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal pathways including apoptosis and cell survival as well as inflammation and immunity. Activated TNF...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC90593

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    BH2 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTP-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Rab GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    apoptotic mitochondrial changes IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to thapsigargin ISO
    Inferred from Sequence Orthology
    more info
     
    dynamin family protein polymerization involved in mitochondrial fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dynamin family protein polymerization involved in mitochondrial fission ISO
    Inferred from Sequence Orthology
    more info
     
    endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    heart contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular distribution of mitochondria IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular distribution of mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    membrane fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane fusion ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial fission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrial fission ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial fragmentation involved in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial fragmentation involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial membrane fission ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion organization ISO
    Inferred from Sequence Orthology
    more info
     
    necroptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    necroptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitochondrial fusion ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome fission ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitochondrial fission ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synaptic vesicle endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    programmed cell death IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex oligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    protein homotetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of ATP metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of autophagy of mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitochondrion organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of peroxisome organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of peroxisome organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein oligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic vesicle endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic vesicle recycling via endosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    brush border IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with clathrin-coated pit ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with mitochondrion-derived vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    presynaptic endocytic zone membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    secretory vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dynamin-1-like protein
    Names
    dymple
    dynamin family member proline-rich carboxyl-terminal domain less
    dynamin-related protein 1
    NP_001021118.1
    NP_001263269.1
    NP_001263270.1
    NP_690029.2
    XP_006522691.1
    XP_006522692.1
    XP_006522693.1
    XP_006522694.1
    XP_006522695.1
    XP_006522696.1
    XP_006522697.1
    XP_006522698.1
    XP_006522699.1
    XP_006522700.1
    XP_006522701.1
    XP_006522702.1
    XP_017172629.1
    XP_017172630.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025947.2NP_001021118.1  dynamin-1-like protein isoform b

      See identical proteins and their annotated locations for NP_001021118.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (b) is shorter than isoform e.
      Source sequence(s)
      AC112943, AI503599, BB006729, BC079635, BY266307
      Consensus CDS
      CCDS27984.1
      UniProtKB/Swiss-Prot
      Q8K1M6
      Related
      ENSMUSP00000023477.7, ENSMUST00000023477.14
      Conserved Domains (4) summary
      cd08771
      Location:23302
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:88692
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:227510
      Dynamin_M; Dynamin central region
      pfam02212
      Location:605693
      GED; Dynamin GTPase effector domain
    2. NM_001276340.1NP_001263269.1  dynamin-1-like protein isoform c

      See identical proteins and their annotated locations for NP_001263269.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (c) is shorter than isoform e.
      Source sequence(s)
      AC112943, AI503599, AK051443, BC079635, BE633575, BG086617, BY309067, CK391623, CK634757, DV652251
      Consensus CDS
      CCDS70689.1
      UniProtKB/Swiss-Prot
      Q8K1M6
      Related
      ENSMUSP00000155155.1, ENSMUST00000230980.1
      Conserved Domains (4) summary
      cd08771
      Location:23308
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:94709
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:233516
      Dynamin_M; Dynamin central region
      pfam02212
      Location:622710
      GED; Dynamin GTPase effector domain
    3. NM_001276341.1NP_001263270.1  dynamin-1-like protein isoform d

      See identical proteins and their annotated locations for NP_001263270.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses an alternate 5' structure, has multiple differences in the coding region and initiates translation at a downstream start codon, compared to variant 6. It encodes isoform d which has a shorter N-terminus compared to isoform e.
      Source sequence(s)
      AC112943, AI503599, BC085158, BE633575, BQ550714, CK391623, CK781757, CN525473, CO432650
      UniProtKB/Swiss-Prot
      Q8K1M6
      Related
      ENSMUSP00000155429.1, ENSMUST00000230022.1
      Conserved Domains (4) summary
      cd08771
      Location:3204
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:1605
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:129412
      Dynamin_M; Dynamin central region
      pfam02212
      Location:518606
      GED; Dynamin GTPase effector domain
    4. NM_001360007.1NP_001346936.1  dynamin-1-like protein isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) represents the longest transcript and encodes the longest isoform (e).
      Source sequence(s)
      AC112943
      Conserved Domains (3) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:245528
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
    5. NM_001360008.1NP_001346937.1  dynamin-1-like protein isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (f) is shorter than isoform e.
      Source sequence(s)
      AC112943
      Conserved Domains (3) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:239522
      Dynamin_M; Dynamin central region
      pfam02212
      Location:655743
      GED; Dynamin GTPase effector domain
    6. NM_001360009.1NP_001346938.1  dynamin-1-like protein isoform g

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (g) is shorter than isoform e.
      Source sequence(s)
      AC112943
      Conserved Domains (3) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:245528
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650738
      GED; Dynamin GTPase effector domain
    7. NM_001360010.1NP_001346939.1  dynamin-1-like protein isoform h

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (h) is shorter than isoform e.
      Source sequence(s)
      AC112943
      Conserved Domains (3) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:239522
      Dynamin_M; Dynamin central region
      pfam02212
      Location:629717
      GED; Dynamin GTPase effector domain
    8. NM_152816.3NP_690029.2  dynamin-1-like protein isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. The encoded isoform (a) is shorter than isoform e.
      Source sequence(s)
      AC112943, AI503599, AK051443, BC079635, BC085158, BY266307
      Consensus CDS
      CCDS27985.1
      UniProtKB/Swiss-Prot
      Q8K1M6
      UniProtKB/TrEMBL
      E9PUD2
      Related
      ENSMUSP00000093945.3, ENSMUST00000096229.10
      Conserved Domains (4) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:101705
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:240523
      Dynamin_M; Dynamin central region
      pfam02212
      Location:618706
      GED; Dynamin GTPase effector domain

    RNA

    1. NR_075074.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) has multiple differences, compared to variant 6. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC112943, AI503599, BB612294, BC085158, CD559921, CD561569, CK341370, CK781757, CN525473

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      16312228..16359044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522637.2XP_006522700.1  dynamin-1-like protein isoform X11

      Conserved Domains (4) summary
      cd08771
      Location:23302
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:88703
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:227510
      Dynamin_M; Dynamin central region
      pfam02212
      Location:616704
      GED; Dynamin GTPase effector domain
    2. XM_006522635.3XP_006522698.1  dynamin-1-like protein isoform X8

      Conserved Domains (4) summary
      cd08771
      Location:23302
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:88718
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:227510
      Dynamin_M; Dynamin central region
      pfam02212
      Location:631719
      GED; Dynamin GTPase effector domain
    3. XM_006522633.2XP_006522696.1  dynamin-1-like protein isoform X6

      Conserved Domains (4) summary
      cd08771
      Location:23302
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:88729
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:227510
      Dynamin_M; Dynamin central region
      pfam02212
      Location:642730
      GED; Dynamin GTPase effector domain
    4. XM_017317140.1XP_017172629.1  dynamin-1-like protein isoform X9

      Conserved Domains (3) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:239522
      Dynamin_M; Dynamin central region
      pfam02212
      Location:629717
      GED; Dynamin GTPase effector domain
    5. XM_006522632.3XP_006522695.1  dynamin-1-like protein isoform X5

      Conserved Domains (4) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:101731
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:240523
      Dynamin_M; Dynamin central region
      pfam02212
      Location:644732
      GED; Dynamin GTPase effector domain
    6. XM_006522629.3XP_006522692.1  dynamin-1-like protein isoform X2

      Conserved Domains (3) summary
      cd08771
      Location:23315
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:239522
      Dynamin_M; Dynamin central region
      pfam02212
      Location:655743
      GED; Dynamin GTPase effector domain
    7. XM_006522631.3XP_006522694.1  dynamin-1-like protein isoform X4

      See identical proteins and their annotated locations for XP_006522694.1

      UniProtKB/Swiss-Prot
      Q8K1M6
      Conserved Domains (4) summary
      cd08771
      Location:23308
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:94735
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:233516
      Dynamin_M; Dynamin central region
      pfam02212
      Location:648736
      GED; Dynamin GTPase effector domain
    8. XM_006522636.2XP_006522699.1  dynamin-1-like protein isoform X10

      See identical proteins and their annotated locations for XP_006522699.1

      Conserved Domains (4) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:107711
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:246529
      Dynamin_M; Dynamin central region
      pfam02212
      Location:624712
      GED; Dynamin GTPase effector domain
    9. XM_006522634.2XP_006522697.1  dynamin-1-like protein isoform X7

      Conserved Domains (4) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:107722
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:246529
      Dynamin_M; Dynamin central region
      pfam02212
      Location:635723
      GED; Dynamin GTPase effector domain
    10. XM_006522630.3XP_006522693.1  dynamin-1-like protein isoform X3

      Conserved Domains (3) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:245528
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650738
      GED; Dynamin GTPase effector domain
    11. XM_006522628.3XP_006522691.1  dynamin-1-like protein isoform X1

      Conserved Domains (3) summary
      cd08771
      Location:23321
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:245528
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
    12. XM_017317141.1XP_017172630.1  dynamin-1-like protein isoform X14

    13. XM_006522638.3XP_006522701.1  dynamin-1-like protein isoform X12

      Related
      ENSMUSP00000111415.2, ENSMUST00000115749.2
      Conserved Domains (4) summary
      cd08771
      Location:1153
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:1580
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:78361
      Dynamin_M; Dynamin central region
      pfam02212
      Location:493581
      GED; Dynamin GTPase effector domain
    14. XM_006522639.1XP_006522702.1  dynamin-1-like protein isoform X13

      Conserved Domains (3) summary
      COG0699
      Location:65436
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:1217
      Dynamin_M; Dynamin central region
      pfam02212
      Location:349437
      GED; Dynamin GTPase effector domain
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