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    Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 77805, updated on 9-Sep-2018

    Summary

    Official Symbol
    Esco1provided by MGI
    Official Full Name
    establishment of sister chromatid cohesion N-acetyltransferase 1provided by MGI
    Primary source
    MGI:MGI:1925055
    See related
    Ensembl:ENSMUSG00000024293 Vega:OTTMUSG00000024447
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A930014I12Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 3.4), bladder adult (RPKM 2.6) and 26 other tissues See more
    Orthologs

    Genomic context

    See Esco1 in Genome Data Viewer
    Location:
    18; 18 A1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (10566507..10610360, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (10566510..10610350, complement)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene RAE1 RNA export 1 homolog pseudogene Neighboring gene growth regulation by estrogen in breast cancer-like Neighboring gene nuclear transport factor 2, pseudogene 2 Neighboring gene small nuclear ribonucleoprotein D1 Neighboring gene abhydrolase domain containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    peptide-lysine-N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-lysine acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    post-translational protein acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    post-translational protein acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-acetyltransferase ESCO1
    Names
    ECO1 homolog 1
    establishment of cohesion 1 homolog 1
    establisment of cohesion 1 homolog 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081222.1NP_001074691.1  N-acetyltransferase ESCO1

      See identical proteins and their annotated locations for NP_001074691.1

      Status: PROVISIONAL

      Source sequence(s)
      AC102441, AC105947
      Consensus CDS
      CCDS37737.1
      UniProtKB/Swiss-Prot
      Q69Z69
      Related
      ENSMUSP00000025142.5, OTTMUSP00000029208, ENSMUST00000025142.11, OTTMUST00000059947
      Conserved Domains (2) summary
      pfam13878
      Location:607646
      zf-C2H2_3; zinc-finger of acetyl-transferase ESCO
      pfam13880
      Location:766828
      Acetyltransf_13; ESCO1/2 acetyl-transferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      10566507..10610360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526353.3XP_006526416.1  N-acetyltransferase ESCO1 isoform X1

      See identical proteins and their annotated locations for XP_006526416.1

      UniProtKB/TrEMBL
      Q3UKT9
      Related
      ENSMUSP00000095274.3, OTTMUSP00000029209, ENSMUST00000097670.9, OTTMUST00000059948
      Conserved Domains (2) summary
      pfam13878
      Location:108147
      zf-C2H2_3; zinc-finger of acetyl-transferase ESCO
      pfam13880
      Location:267329
      Acetyltransf_13; ESCO1/2 acetyl-transferase

    RNA

    1. XR_001782402.1 RNA Sequence

    2. XR_001782403.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_144542.1: Suppressed sequence

      Description
      NM_144542.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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