Format

Send to:

Choose Destination
    • Showing Current items.

    Klf7 Kruppel-like factor 7 (ubiquitous) [ Mus musculus (house mouse) ]

    Gene ID: 93691, updated on 9-Sep-2018

    Summary

    Official Symbol
    Klf7provided by MGI
    Official Full Name
    Kruppel-like factor 7 (ubiquitous)provided by MGI
    Primary source
    MGI:MGI:1935151
    See related
    Ensembl:ENSMUSG00000025959 Vega:OTTMUSG00000013919
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9830124P08Rik
    Expression
    Broad expression in CNS E18 (RPKM 10.9), whole brain E14.5 (RPKM 9.3) and 26 other tissues See more
    Orthologs

    Genomic context

    See Klf7 in Genome Data Viewer
    Location:
    1; 1 C2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (64029448..64122328, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (64082237..64167963, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene carboxypeptidase O pseudogene Neighboring gene predicted gene 13749 Neighboring gene microRNA 6899 Neighboring gene predicted gene, 35880 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene 1_583.1 Neighboring gene predicted gene, 39654

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Adipogenesis genes, organism-specific biosystem (from WikiPathways)
      Adipogenesis genes, organism-specific biosystemThe different classes of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compos...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033563.2NP_291041.2  Krueppel-like factor 7

      See identical proteins and their annotated locations for NP_291041.2

      Status: PROVISIONAL

      Source sequence(s)
      BC019604
      Consensus CDS
      CCDS15003.1
      UniProtKB/Swiss-Prot
      Q99JB0
      Related
      ENSMUSP00000109720.2, OTTMUSP00000014823, ENSMUST00000114086.7, OTTMUST00000033149
      Conserved Domains (3) summary
      COG5048
      Location:211283
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:223242
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:278300
      zf-C2H2; Zinc finger, C2H2 type

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      64029448..64122328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496352.3XP_006496415.1  Krueppel-like factor 7 isoform X1

      See identical proteins and their annotated locations for XP_006496415.1

      Conserved Domains (3) summary
      COG5048
      Location:223281
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:223242
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:265290
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006496353.2XP_006496416.1  Krueppel-like factor 7 isoform X1

      See identical proteins and their annotated locations for XP_006496416.1

      Conserved Domains (3) summary
      COG5048
      Location:223281
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:223242
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:265290
      zf-H2C2_2; Zinc-finger double domain
    3. XM_006496354.3XP_006496417.1  Krueppel-like factor 7 isoform X2

      See identical proteins and their annotated locations for XP_006496417.1

      UniProtKB/Swiss-Prot
      Q99JB0
      Conserved Domains (3) summary
      COG5048
      Location:211283
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:223242
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:278300
      zf-C2H2; Zinc finger, C2H2 type
    4. XM_006496351.3XP_006496414.1  Krueppel-like factor 7 isoform X1

      See identical proteins and their annotated locations for XP_006496414.1

      Conserved Domains (3) summary
      COG5048
      Location:223281
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:223242
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:265290
      zf-H2C2_2; Zinc-finger double domain
    Support Center