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    Cntnap5b contactin associated protein-like 5B [ Mus musculus (house mouse) ]

    Gene ID: 241175, updated on 3-Apr-2018

    Summary

    Official Symbol
    Cntnap5bprovided by MGI
    Official Full Name
    contactin associated protein-like 5Bprovided by MGI
    Primary source
    MGI:MGI:3664583
    See related
    Ensembl:ENSMUSG00000067028 Vega:OTTMUSG00000048875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Caspr5-2; C230078M14Rik
    Expression
    Biased expression in testis adult (RPKM 3.6), CNS E18 (RPKM 1.8) and 5 other tissues See more

    Genomic context

    See Cntnap5b in Genome Data Viewer
    Location:
    1; 1 E1.1
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (99772245..100490599)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (101669342..102382519)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene 7967 Neighboring gene predicted gene, 18248 Neighboring gene thioredoxin peroxidase, pseudogene 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene predicted gene, 41923 Neighboring gene baculoviral IAP repeat-containing 2 pseudogene Neighboring gene survival motor neuron 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    contactin-associated protein like 5-2
    Names
    cell recognition molecule Caspr5-2
    cell recognition molecule Caspr5b
    contactin-associated protein-like 5b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172851.2NP_766439.2  contactin-associated protein like 5-2 precursor

      See identical proteins and their annotated locations for NP_766439.2

      Status: VALIDATED

      Source sequence(s)
      AC161355, BN000866
      Consensus CDS
      CCDS35682.1
      UniProtKB/Swiss-Prot
      Q0V8T8
      Related
      ENSMUSP00000083944.3, OTTMUSP00000067888, ENSMUST00000086738.9, OTTMUST00000124972
      Conserved Domains (6) summary
      smart00231
      Location:56174
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      smart00282
      Location:205338
      LamG; Laminin G domain
      cd00057
      Location:56173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:779923
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:550581
      EGF; EGF-like domain
      pfam02210
      Location:395521
      Laminin_G_2; Laminin G domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      99772245..100490599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529594.3XP_006529657.1  contactin-associated protein like 5-2 isoform X1

      Conserved Domains (6) summary
      smart00231
      Location:56174
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      smart00282
      Location:205338
      LamG; Laminin G domain
      cd00057
      Location:56173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:780924
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:551582
      EGF; EGF-like domain
      pfam02210
      Location:396522
      Laminin_G_2; Laminin G domain
    2. XM_006529595.3XP_006529658.3  contactin-associated protein like 5-2 isoform X2

    3. XM_011248005.2XP_011246307.1  contactin-associated protein like 5-2 isoform X3

      Conserved Domains (3) summary
      cd00110
      Location:150294
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:318351
      EGF; EGF-like domain
      pfam02210
      Location:402530
      Laminin_G_2; Laminin G domain
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