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    Nckap5 NCK-associated protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 210356, updated on 9-Sep-2018

    Summary

    Official Symbol
    Nckap5provided by MGI
    Official Full Name
    NCK-associated protein 5provided by MGI
    Primary source
    MGI:MGI:2686394
    See related
    Ensembl:ENSMUSG00000049690 Vega:OTTMUSG00000030251
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nap5; Erih1; Erih2; Gm1548; 8430408F21; D130011D22Rik; E030049G20Rik
    Expression
    Biased expression in lung adult (RPKM 4.1), CNS E18 (RPKM 1.4) and 13 other tissues See more
    Orthologs

    Genomic context

    See Nckap5 in Genome Data Viewer
    Location:
    1; 1 E3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (125913636..126830900, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (127810213..128727209, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 39 Neighboring gene predicted gene, 41943 Neighboring gene Ly6/Plaur domain containing 1 Neighboring gene predicted gene, 35562 Neighboring gene uncharacterized LOC102639337 Neighboring gene predicted gene, 41945

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC90557

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    microtubule bundle formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    nck-associated protein 5
    Names
    peripheral clock protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081756.1NP_001075225.1  nck-associated protein 5 isoform 1

      See identical proteins and their annotated locations for NP_001075225.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
      Source sequence(s)
      AK053243, BC066095, CN700744
      Consensus CDS
      CCDS35695.1
      UniProtKB/TrEMBL
      E9QAE1, Q6NZK2, Q8C6S8
      Related
      ENSMUSP00000108202.1, ENSMUST00000112583.7
      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. NM_172484.3NP_766072.2  nck-associated protein 5 isoform 2

      See identical proteins and their annotated locations for NP_766072.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and a protein (isoform 2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK053243, BC066095
      Consensus CDS
      CCDS48345.1
      UniProtKB/TrEMBL
      Q6NZK2, Q8C6S8
      Related
      ENSMUSP00000125624.1, OTTMUSP00000039157, ENSMUST00000161954.7, OTTMUST00000074895
      Conserved Domains (2) summary
      pfam15246
      Location:13631665
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:289
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    3. NM_176957.3NP_795931.2  nck-associated protein 5 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks several segments in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 3) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AK053243, BC066095, CN700744
      Consensus CDS
      CCDS48346.1
      UniProtKB/TrEMBL
      E9Q3G9, Q6NZK2, Q8C6S8
      Related
      ENSMUSP00000092192.3, ENSMUST00000094609.9
      Conserved Domains (1) summary
      pfam15246
      Location:271363
      NCKAP5; Nck-associated protein 5, Peripheral clock protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      125913636..126830900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529326.3XP_006529389.1  nck-associated protein 5 isoform X1

      See identical proteins and their annotated locations for XP_006529389.1

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. XM_011247963.2XP_011246265.1  nck-associated protein 5 isoform X13

      Conserved Domains (2) summary
      pfam15246
      Location:14651767
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    3. XM_006529331.3XP_006529394.1  nck-associated protein 5 isoform X7

      Conserved Domains (2) summary
      pfam15246
      Location:13671669
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    4. XM_006529325.3XP_006529388.1  nck-associated protein 5 isoform X1

      See identical proteins and their annotated locations for XP_006529388.1

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    5. XM_006529329.3XP_006529392.1  nck-associated protein 5 isoform X2

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    6. XM_011247958.2XP_011246260.1  nck-associated protein 5 isoform X3

      Conserved Domains (2) summary
      pfam15246
      Location:14061708
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:7132
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    7. XM_006529332.3XP_006529395.1  nck-associated protein 5 isoform X8

      See identical proteins and their annotated locations for XP_006529395.1

      Conserved Domains (2) summary
      pfam15246
      Location:13631665
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:289
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    8. XM_011247959.2XP_011246261.1  nck-associated protein 5 isoform X5

      Conserved Domains (2) summary
      pfam15246
      Location:13981700
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:37124
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    9. XM_017319542.1XP_017175031.1  nck-associated protein 5 isoform X8

      Conserved Domains (2) summary
      pfam15246
      Location:13631665
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:289
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    10. XM_011247960.2XP_011246262.1  nck-associated protein 5 isoform X6

      Conserved Domains (2) summary
      pfam15246
      Location:13911693
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:30117
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    11. XM_006529333.3XP_006529396.1  nck-associated protein 5 isoform X9

      Conserved Domains (2) summary
      pfam15246
      Location:13671669
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    12. XM_006529330.3XP_006529393.1  nck-associated protein 5 isoform X4

      See identical proteins and their annotated locations for XP_006529393.1

      UniProtKB/TrEMBL
      E9QAE1
      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    13. XM_006529334.3XP_006529397.1  nck-associated protein 5 isoform X10

      See identical proteins and their annotated locations for XP_006529397.1

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    14. XM_006529336.3XP_006529399.1  nck-associated protein 5 isoform X11

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    15. XM_011247962.2XP_011246264.1  nck-associated protein 5 isoform X12

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    16. XM_006529335.3XP_006529398.1  nck-associated protein 5 isoform X10

      See identical proteins and their annotated locations for XP_006529398.1

      Conserved Domains (2) summary
      pfam15246
      Location:14311733
      NCKAP5; Nck-associated protein 5, Peripheral clock protein
      cl23720
      Location:32157
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
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