Format

Send to:

Choose Destination
    • Showing Current items.

    Nfyb nuclear transcription factor-Y beta [ Mus musculus (house mouse) ]

    Gene ID: 18045, updated on 2-Oct-2018

    Summary

    Official Symbol
    Nfybprovided by MGI
    Official Full Name
    nuclear transcription factor-Y betaprovided by MGI
    Primary source
    MGI:MGI:97317
    See related
    Ensembl:ENSMUSG00000020248 Vega:OTTMUSG00000032747
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cbf-A; AA985999
    Expression
    Broad expression in CNS E11.5 (RPKM 15.1), CNS E14 (RPKM 12.4) and 24 other tissues See more
    Orthologs

    Genomic context

    See Nfyb in Genome Data Viewer
    Location:
    10 C1; 10 40.25 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (82748700..82764144, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (82211445..82226886, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1190007I07 gene Neighboring gene thymine DNA glycosylase Neighboring gene glycosyltransferase 8 domain containing 2 Neighboring gene host cell factor C2 Neighboring gene RIKEN cDNA 1700028I16 gene Neighboring gene thioredoxin reductase 1 Neighboring gene predicted gene, 38560

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    repressing transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    contributes_to transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to transcription regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    CCAAT-binding factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    CCAAT-binding factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II transcription factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein-DNA complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor complex IC
    Inferred by Curator
    more info
    PubMed 

    General protein information

    Preferred Names
    nuclear transcription factor Y subunit beta
    Names
    CAAT box DNA-binding protein subunit B
    NF-YB
    nuclear transcription factor Y subunit B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010914.2NP_035044.1  nuclear transcription factor Y subunit beta

      See identical proteins and their annotated locations for NP_035044.1

      Status: VALIDATED

      Source sequence(s)
      AK010762, AK079209, BB031987, BB858171
      Consensus CDS
      CCDS48654.1
      UniProtKB/Swiss-Prot
      P63139
      UniProtKB/TrEMBL
      Q8C590
      Related
      ENSMUSP00000122403.1, OTTMUSP00000043614, ENSMUST00000130911.7, OTTMUST00000081491
      Conserved Domains (1) summary
      pfam00808
      Location:59122
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      82748700..82764144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243380.2XP_011241682.1  nuclear transcription factor Y subunit beta isoform X2

      See identical proteins and their annotated locations for XP_011241682.1

      Conserved Domains (1) summary
      pfam00808
      Location:247
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone
    2. XM_011243379.2XP_011241681.1  nuclear transcription factor Y subunit beta isoform X1

      See identical proteins and their annotated locations for XP_011241681.1

      UniProtKB/Swiss-Prot
      P63139
      Conserved Domains (1) summary
      pfam00808
      Location:59122
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone
    3. XM_011243381.2XP_011241683.1  nuclear transcription factor Y subunit beta isoform X2

      See identical proteins and their annotated locations for XP_011241683.1

      Conserved Domains (1) summary
      pfam00808
      Location:247
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone
    Support Center